Development of a novel single vessel processor

part 2: particle size reduction characteristics

G R Kay, J N Staniforth, M J Tobyn, Linda B Newnes, Stuart A MacGregor

Research output: Contribution to journalArticle

Abstract

Objective.: To characterise the effectiveness of a novel Single Vessel Processor (SVP) in reducing the particle size of lactose granules for use in tablet production. Conclusions.Particle size reduction of granular lactose was found to be rapid for the batch size investigated; the speed and extent of size reduction was considered to be at least equivalent to that which could be attained using conventional processing techniques. It is envisaged that greater size reduction of primary crystallites could be obtained by increasing the nozzle air pressures and/or altering the geometry of the novel SVP
Original languageEnglish
Pages (from-to)S-416
JournalPharmaceutical Research
Volume14
Issue number11
Publication statusPublished - 1997

Fingerprint

Lactose
Particle Size
Particle size
Air Pressure
Tablets
Crystallites
Nozzles
Geometry
Processing
Air

Keywords

  • Powder Processing pharmaceutics Design size reduction

Cite this

Kay, G. R., Staniforth, J. N., Tobyn, M. J., Newnes, L. B., & MacGregor, S. A. (1997). Development of a novel single vessel processor: part 2: particle size reduction characteristics. Pharmaceutical Research, 14(11), S-416.

Development of a novel single vessel processor : part 2: particle size reduction characteristics. / Kay, G R; Staniforth, J N; Tobyn, M J; Newnes, Linda B; MacGregor, Stuart A.

In: Pharmaceutical Research, Vol. 14, No. 11, 1997, p. S-416.

Research output: Contribution to journalArticle

Kay, GR, Staniforth, JN, Tobyn, MJ, Newnes, LB & MacGregor, SA 1997, 'Development of a novel single vessel processor: part 2: particle size reduction characteristics', Pharmaceutical Research, vol. 14, no. 11, pp. S-416.
Kay, G R ; Staniforth, J N ; Tobyn, M J ; Newnes, Linda B ; MacGregor, Stuart A. / Development of a novel single vessel processor : part 2: particle size reduction characteristics. In: Pharmaceutical Research. 1997 ; Vol. 14, No. 11. pp. S-416.
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