Development and assessment of a computerized index of clinical disease activity in systemic lupus erythematosus

D. P. M. Symmons, J. S. Coppock, P. A. Bacon, B. Bresnihan, D. A. Isenberg, P. Maddison, N. McHugh, M. L. Snaith, A. S. Zoma

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Abstract

Five centres in Great Britain and the Republic of Ireland have collaborated to produce a computerized index of clinical disease activity in systemic lupus erythematosus, based on the principle of the physician's intention to treat. The index assesses separately eight organ-based systems. The index has proved quick and easy to use despite a comprehensive database and compares favourably with two other indices of disease activity. It has great potential for use in multicentre studies of disease outcome and new therapies in systemic lupus erythematosus.
Original languageEnglish
Pages (from-to)927-937
Number of pages11
JournalThe Quarterly Journal of Medicine
Volume69
Issue number258
Publication statusPublished - Nov 1988

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Keywords

  • Humans
  • Lupus Erythematosus, Systemic
  • Medical Informatics Computing

Cite this

Symmons, D. P. M., Coppock, J. S., Bacon, P. A., Bresnihan, B., Isenberg, D. A., Maddison, P., ... Zoma, A. S. (1988). Development and assessment of a computerized index of clinical disease activity in systemic lupus erythematosus. The Quarterly Journal of Medicine, 69(258), 927-937.