Abstract
Methods for the detection and functionalisation of S-nitrosylated polypeptides are disclosed, and more particularly to methods and kits in which an S-nitrosothiol (SNO) group present in a polypeptide is reacted with an SNO binding (SNOB) reagent via a free radical reaction, the SNOB reagent containing a label or transfer moiety.
| Original language | English |
|---|---|
| Patent number | WO2009024791 (A1) |
| IPC | G01N33/68 |
| Priority date | 21/08/07 |
| Filing date | 21/08/08 |
| Publication status | Published - 26 Feb 2009 |