Abstract
Methods for the detection and functionalisation of S-nitrosylated polypeptides are disclosed, and more particularly to methods and kits in which an S-nitrosothiol (SNO) group present in a polypeptide is reacted with an SNO binding (SNOB) reagent via a free radical reaction, the SNOB reagent containing a label or transfer moiety.
Original language | English |
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Patent number | WO2009024791 (A1) |
IPC | G01N33/68 |
Priority date | 21/08/07 |
Filing date | 21/08/08 |
Publication status | Published - 26 Feb 2009 |