Delivering transformative action in paediatric pain: a Lancet Child & Adolescent Health Commission

Christopher Eccleston; Emma Fisher; Richard F. Howard; Rebeccah Slater; Paula Forgeron; Tonya M. Palermo; Kathryn Birnie; Brian J. Anderson; Christine T. Chambers; Geert Crombez; Gustaf Ljungman; Isabel Jordan; Zachary Jordan; Catriona Roberts; Neil Schechter; Christine Sieberg; Dick Tibboel; Suellen M. Walker; Dominic Wilkinson; Chantal Wood

doi:10.1016/S2352-4642(20)30277-7

Delivering transformative action in paediatric pain: a Lancet Child & Adolescent Health Commission

Christopher Eccleston, Emma Fisher, Richard F. Howard, Rebeccah Slater, Paula Forgeron, Tonya M. Palermo, Kathryn Birnie, Brian J. Anderson, Christine T. Chambers, Geert Crombez, Gustaf Ljungman, Isabel Jordan, Zachary Jordan, Catriona Roberts, Neil Schechter, Christine Sieberg, Dick Tibboel, Suellen M. Walker, Dominic Wilkinson, Chantal Wood

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Abstract

Every infant, child, and adolescent will experience pain at times throughout their life. Childhood pain ranges from acute to chronic, and includes procedural, disease-related, breakthrough, and other types of pain. Despite its ubiquity, pain is a major challenge for individuals, families, health-care professionals, and societies. As a private mental experience, pain is often hidden and can go undiscussed or ignored. Undertreated, unrecognised, or poorly managed pain in childhood leads to important and long-lasting negative consequences that continue into adulthood, including continued chronic pain, disability, and distress. This undertreatment of pain should not continue, as there are available tools, expertise, and evidence to provide better treatment for childhood pain.

Original language	English
Pages (from-to)	P47-P87
Journal	The Lancet Child & Adolescent Health
Volume	5
Issue number	1
Early online date	13 Oct 2020
DOIs	https://doi.org/10.1016/S2352-4642(20)30277-7
Publication status	Published - 1 Jan 2021

Funding

We thank The MayDay Fund (New York City, NY, USA) and Versus Arthritis (London, UK) for their financial support for this manuscript, which included funding meetings to discuss the Commission. The funders had no other role in the development of the Commission. CE and RFH report grants from National Institute for Health Research UK. EF is a Versus Arthritis Career Development Fellow. CTC is funded by the Canadian Institutes of Health Research and other granting agencies. CS is funded by a K23 Award from the US National Institutes of Health (GM123372), a grant from the Boston Center for Endometriosis/Marriott Foundation Investigator Award, and a grant from the Department of Defense (W81XWH1910560). We also thank Rachel Deere (University of Bath, Bath, UK) for her help in preparing the manuscript for submission, as well as Andrew Moore (Newton Ferrers, Devon, UK) and Neil O'Connell (Brunell University London, London, UK) for their comments on an earlier version of the manuscript. RFH reports grants from Great Ormond Street Hospital Children's Charity, SPARKS Charity, Louis Dundas Foundation Medical Charity; and personal fees (for research consultancy) from Grünenthal and Regeneron UK, and personal fees (for regulatory consultancy) from Wockhardt UK, outside the submitted work. KB is Assistant Scientific Director of Solutions for Kids in Pain and declares no competing interests. CTC is Scientific Director of the Canadian Institutes of Health Research Institute of Human Development, Child and Youth Health, and Scientific Director of Solutions for Kids in Pain, and declares no competing interests. SMW reports grants from Sintetica, personal fees from Advisory Board for Regeneron Pharmaceuticals, and speaking fees from Takeda Pharmaceuticals for her presentation on pain research, outside the submitted work. All other authors declare no competing interests.

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10.1016/S2352-4642(20)30277-7

Lancet_Commission_R4_accepted_with_ES.PDFAccepted author manuscript, 1.11 MBLicence: CC BY-NC-ND

1 Finished
1 Active

Fellowship - Identifying Children who Develop Chronic Pain after a Fracture Injury
Fisher, E. (PI)
Versus Arthritis
4/02/19 → 5/04/26
Project: UK charity
Addressing the Unmet Need of Chronic Pain: Providing the Evidence for Treatments of Pain
Eccleston, C. (PI)
National Institute for Health Research
1/07/14 → 31/10/18
Project: Central government, health and local authorities

Cite this

Eccleston, C., Fisher, E., Howard, R. F., Slater, R., Forgeron, P., Palermo, T. M., Birnie, K., Anderson, B. J., Chambers, C. T., Crombez, G., Ljungman, G., Jordan, I., Jordan, Z., Roberts, C., Schechter, N., Sieberg, C., Tibboel, D., Walker, S. M., Wilkinson, D., & Wood, C. (2021). Delivering transformative action in paediatric pain: a Lancet Child & Adolescent Health Commission. The Lancet Child & Adolescent Health, 5(1), P47-P87. https://doi.org/10.1016/S2352-4642(20)30277-7

Eccleston, C , Fisher, E, Howard, RF, Slater, R, Forgeron, P, Palermo, TM, Birnie, K, Anderson, BJ, Chambers, CT, Crombez, G, Ljungman, G, Jordan, I, Jordan, Z, Roberts, C, Schechter, N, Sieberg, C, Tibboel, D, Walker, SM, Wilkinson, D & Wood, C 2021, 'Delivering transformative action in paediatric pain: a Lancet Child & Adolescent Health Commission', The Lancet Child & Adolescent Health, vol. 5, no. 1, pp. P47-P87. https://doi.org/10.1016/S2352-4642(20)30277-7

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Delivering transformative action in paediatric pain: a Lancet Child & Adolescent Health Commission

Abstract

Funding

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Projects

Fellowship - Identifying Children who Develop Chronic Pain after a Fracture Injury

Addressing the Unmet Need of Chronic Pain: Providing the Evidence for Treatments of Pain

Cite this