Deep tissue contractility sensing with biointegrated microlasers

Marcel Schubert, Lewis Woolfson, Isla R.M. Barnard, Amy M. Dorward, Becky Casement, Soraya Caixeiro, Andrew Morton, Gavin B. Robertson, Paul L. Appleton, Gareth B. Miles, Carl S. Tucker, Samantha J. Pitt, Malte C. Gather

Research output: Chapter or section in a book/report/conference proceedingChapter or section

Abstract

Characterizing single cell contractility in the beating heart is strongly limited by light scattering and extreme tissue dynamics. Here, we use tissue-integrated microlasers to measure contractility in live zebrafish and living myocardial slices at a depth several times deeper than multiphoton microscopy-based techniques.

Original languageEnglish
Title of host publicationOSA Technical Digest
DOIs
Publication statusPublished - 16 Apr 2021
EventNovel Techniques in Microscopy, NTM 2021 - Part of Biophotonics Congress: Optics in the Life Sciences 2021 - Virtual, Online, USA United States
Duration: 12 Apr 202116 Apr 2021

Publication series

NameOptics InfoBase Conference Papers
ISSN (Print)2162-2701

Conference

ConferenceNovel Techniques in Microscopy, NTM 2021 - Part of Biophotonics Congress: Optics in the Life Sciences 2021
Country/TerritoryUSA United States
CityVirtual, Online
Period12/04/2116/04/21

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Mechanics of Materials

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