Cyclic Adenosine Diphosphate Ribose Analogues for Modulating T Cell Activity

Barry Potter (Inventor), Andreas H Guse (Inventor), Hendrik Schulze-Koops (Inventor), Ingeborg Berg (Inventor), Georg W Mayr (Inventor)

Research output: Patent

Abstract

Compounds capable of antagonising a sustained cADPR-mediated rise in intracellular Ca<2+> levels in a T cell, said rise being in response to stimulation of the T cell receptor/CD3 complex of the T cell, methods for identifying the same and their use in modulating T cell activity are described. The preferred compounds are cyclic adenosine diphosphate ribose analogues.
Original languageEnglish
Patent numberWO0037089 (A1)
IPCG01N33/50
Publication statusPublished - 29 Jun 2000

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Cyclic ADP-Ribose
T-Lymphocytes
CD3 Antigens
T-Cell Antigen Receptor

Cite this

Potter, B., Guse, A. H., Schulze-Koops , H., Berg , I., & Mayr, G. W. (2000). IPC No. G01N33/50. Cyclic Adenosine Diphosphate Ribose Analogues for Modulating T Cell Activity. (Patent No. WO0037089 (A1)).

Cyclic Adenosine Diphosphate Ribose Analogues for Modulating T Cell Activity. / Potter, Barry (Inventor); Guse, Andreas H (Inventor); Schulze-Koops , Hendrik (Inventor); Berg , Ingeborg (Inventor); Mayr, Georg W (Inventor).

IPC No.: G01N33/50. Patent No.: WO0037089 (A1).

Research output: Patent

Potter, B, Guse, AH, Schulze-Koops , H, Berg , I & Mayr, GW 2000, Cyclic Adenosine Diphosphate Ribose Analogues for Modulating T Cell Activity, Patent No. WO0037089 (A1), IPC No. G01N33/50.
Potter B, Guse AH, Schulze-Koops H, Berg I, Mayr GW, inventors. Cyclic Adenosine Diphosphate Ribose Analogues for Modulating T Cell Activity. G01N33/50. 2000 Jun 29.
Potter, Barry (Inventor) ; Guse, Andreas H (Inventor) ; Schulze-Koops , Hendrik (Inventor) ; Berg , Ingeborg (Inventor) ; Mayr, Georg W (Inventor). / Cyclic Adenosine Diphosphate Ribose Analogues for Modulating T Cell Activity. IPC No.: G01N33/50. Patent No.: WO0037089 (A1).
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