### Abstract

Original language | English |
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Patent number | WO9843992 (A1) |

IPC | C07H19/20 |

Publication status | Published - 8 Oct 1998 |

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### Cite this

*WO9843992 (A1)*).

**Cyclic Adenosine Diphosphate Ribose Analogues.** / Galione, Antony (Inventor); Potter, Barry (Inventor).

Research output: Patent

*Cyclic Adenosine Diphosphate Ribose Analogues*, Patent No. WO9843992 (A1), IPC No. C07H19/20.

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TY - PAT

T1 - Cyclic Adenosine Diphosphate Ribose Analogues

AU - Galione, Antony

AU - Potter, Barry

PY - 1998/10/8

Y1 - 1998/10/8

N2 - A compound having formula (1) where at least one of X<3> and X<7> is CR and any remaining X<3> or X<7> is N; Y is halo, C1-C20 hydrocarbon, NR2, OR, SR, nitro or carboxyl; R is H or C1-C20 hydrocarbon and R groups can be the same or different; and one or each Z represents H or one Z is a cageing group. The compound 7-deaza-8-bromo-cyclic adenosine 5'-diphosphate ribose has been shown to be a stable hydrolysis-resistant cADPR antagonist.

AB - A compound having formula (1) where at least one of X<3> and X<7> is CR and any remaining X<3> or X<7> is N; Y is halo, C1-C20 hydrocarbon, NR2, OR, SR, nitro or carboxyl; R is H or C1-C20 hydrocarbon and R groups can be the same or different; and one or each Z represents H or one Z is a cageing group. The compound 7-deaza-8-bromo-cyclic adenosine 5'-diphosphate ribose has been shown to be a stable hydrolysis-resistant cADPR antagonist.

M3 - Patent

M1 - WO9843992 (A1)

ER -