Correlation between inclination of the acetabular component and metal ion levels in metal-on-metal hip resurfacing replacement

R. De Haan, C. Pattyn, H. S. Gill, D. W. Murray, P. A. Campbell, K. De Smet

Research output: Contribution to journalArticle

399 Citations (Scopus)

Abstract

We examined the relationships between the serum levels of chromium and cobalt ions and the inclination angle of the acetabular component and the level of activity in 214 patients implanted with a metal-on-metal resurfacing hip replacement. Each patient had a single resurfacing and no other metal in their body. All serum measurements were performed at a minimum of one year after operation. The inclination of the acetabular component was considered to be steep if the abduction angle was greater than 55 degrees. There were significantly higher levels of metal ions in patients with steeply-inclined components (p = 0.002 for chromium, p = 0.003 for cobalt), but no correlation was found between the level of activity and the concentration of metal ions. A highly significant (p <0.001) correlation with the arc of cover was found. Arcs of cover of less than 10 mm were correlated with a greater risk of high concentrations of serum metal ions. The arc of coverage was also related to the design of the component and to size as well as to the abduction angle of the acetabular component. Steeply-inclined acetabular components, with abduction angles greater than 55 degrees, combined with a small size of component are likely to give rise to higher serum levels of cobalt and chromium ions. This is probably due to a greater risk of edge-loading.
Original languageEnglish
Pages (from-to)1291-1297
Number of pages7
JournalJournal of Bone and Joint Surgery - British Volume
Volume90
Issue number10
DOIs
Publication statusPublished - Oct 2008

Fingerprint

Hip
Metals
Ions
Chromium
Cobalt
Serum

Cite this

Correlation between inclination of the acetabular component and metal ion levels in metal-on-metal hip resurfacing replacement. / De Haan, R.; Pattyn, C.; Gill, H. S.; Murray, D. W.; Campbell, P. A.; De Smet, K.

In: Journal of Bone and Joint Surgery - British Volume, Vol. 90, No. 10, 10.2008, p. 1291-1297.

Research output: Contribution to journalArticle

@article{f95cfa29da7543dba0fa25c703e3e4bb,
title = "Correlation between inclination of the acetabular component and metal ion levels in metal-on-metal hip resurfacing replacement",
abstract = "We examined the relationships between the serum levels of chromium and cobalt ions and the inclination angle of the acetabular component and the level of activity in 214 patients implanted with a metal-on-metal resurfacing hip replacement. Each patient had a single resurfacing and no other metal in their body. All serum measurements were performed at a minimum of one year after operation. The inclination of the acetabular component was considered to be steep if the abduction angle was greater than 55 degrees. There were significantly higher levels of metal ions in patients with steeply-inclined components (p = 0.002 for chromium, p = 0.003 for cobalt), but no correlation was found between the level of activity and the concentration of metal ions. A highly significant (p <0.001) correlation with the arc of cover was found. Arcs of cover of less than 10 mm were correlated with a greater risk of high concentrations of serum metal ions. The arc of coverage was also related to the design of the component and to size as well as to the abduction angle of the acetabular component. Steeply-inclined acetabular components, with abduction angles greater than 55 degrees, combined with a small size of component are likely to give rise to higher serum levels of cobalt and chromium ions. This is probably due to a greater risk of edge-loading.",
author = "{De Haan}, R. and C. Pattyn and Gill, {H. S.} and Murray, {D. W.} and Campbell, {P. A.} and {De Smet}, K.",
year = "2008",
month = "10",
doi = "10.1302/0301-620X.90B10.20533",
language = "English",
volume = "90",
pages = "1291--1297",
journal = "Journal of Bone and Joint Surgery - British Volume",
issn = "0301-620X",
publisher = "British Editorial Society of Bone and Joint Surgery",
number = "10",

}

TY - JOUR

T1 - Correlation between inclination of the acetabular component and metal ion levels in metal-on-metal hip resurfacing replacement

AU - De Haan, R.

AU - Pattyn, C.

AU - Gill, H. S.

AU - Murray, D. W.

AU - Campbell, P. A.

AU - De Smet, K.

PY - 2008/10

Y1 - 2008/10

N2 - We examined the relationships between the serum levels of chromium and cobalt ions and the inclination angle of the acetabular component and the level of activity in 214 patients implanted with a metal-on-metal resurfacing hip replacement. Each patient had a single resurfacing and no other metal in their body. All serum measurements were performed at a minimum of one year after operation. The inclination of the acetabular component was considered to be steep if the abduction angle was greater than 55 degrees. There were significantly higher levels of metal ions in patients with steeply-inclined components (p = 0.002 for chromium, p = 0.003 for cobalt), but no correlation was found between the level of activity and the concentration of metal ions. A highly significant (p <0.001) correlation with the arc of cover was found. Arcs of cover of less than 10 mm were correlated with a greater risk of high concentrations of serum metal ions. The arc of coverage was also related to the design of the component and to size as well as to the abduction angle of the acetabular component. Steeply-inclined acetabular components, with abduction angles greater than 55 degrees, combined with a small size of component are likely to give rise to higher serum levels of cobalt and chromium ions. This is probably due to a greater risk of edge-loading.

AB - We examined the relationships between the serum levels of chromium and cobalt ions and the inclination angle of the acetabular component and the level of activity in 214 patients implanted with a metal-on-metal resurfacing hip replacement. Each patient had a single resurfacing and no other metal in their body. All serum measurements were performed at a minimum of one year after operation. The inclination of the acetabular component was considered to be steep if the abduction angle was greater than 55 degrees. There were significantly higher levels of metal ions in patients with steeply-inclined components (p = 0.002 for chromium, p = 0.003 for cobalt), but no correlation was found between the level of activity and the concentration of metal ions. A highly significant (p <0.001) correlation with the arc of cover was found. Arcs of cover of less than 10 mm were correlated with a greater risk of high concentrations of serum metal ions. The arc of coverage was also related to the design of the component and to size as well as to the abduction angle of the acetabular component. Steeply-inclined acetabular components, with abduction angles greater than 55 degrees, combined with a small size of component are likely to give rise to higher serum levels of cobalt and chromium ions. This is probably due to a greater risk of edge-loading.

UR - http://www.scopus.com/inward/record.url?scp=53849111555&partnerID=8YFLogxK

UR - http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18827237

UR - http://dx.doi.org/10.1302/0301-620X.90B10.20533

U2 - 10.1302/0301-620X.90B10.20533

DO - 10.1302/0301-620X.90B10.20533

M3 - Article

VL - 90

SP - 1291

EP - 1297

JO - Journal of Bone and Joint Surgery - British Volume

JF - Journal of Bone and Joint Surgery - British Volume

SN - 0301-620X

IS - 10

ER -