11 Citations (SciVal)
77 Downloads (Pure)


Objective: The literature on testosterone (T) in men reports diverse correlates of T, some with minimal empirical support and most with little indication of how they change with advancing age. We test eight putative correlations across age.

Method: Correlations were tested on a large sample of British men.

Results: Seven of eight correlations replicated. Most change across men's life courses. The diurnal cycle of T is considerably weaker among older than younger men. Single men have higher T than married men of the same age; however, this difference lessens as men get older. Elevated T among smokers is less pronounced as men age. The inverse relationship between obesity and T is sustained across the adult age range. The lessening of T with age is well established, however there is disagreement about the course of decline. We find T having a steep decline around age 30, with possibly a rebound around age 50, after which levels remain roughly constant. Correlations involving health become stronger among older men. After age 30 or 40, the inverse relationships between T and HbA1c, diabetes, and metabolic syndrome all become increasingly significant, though not necessarily strong in magnitude.

Conclusion: Most putative correlates of T are replicated. There is a basis here for the generalization that among older men, those healthy have higher T than those who are not, but not a lot higher.
Original languageEnglish
Pages (from-to)29-40
JournalThe Aging Male
Issue number1
Publication statusPublished - 4 Jan 2022

Bibliographical note

Funding Information:
This research is unfunded. The authors thank Peter Eibich, Amanda Hughes, Bob Josephs, and Oliver Schulteiss for constructive comments on a preliminary version of the article, as well as anonymous reviewers for later comments.

Publisher Copyright:
© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.


Dive into the research topics of 'Correlates of testosterone change as men age'. Together they form a unique fingerprint.

Cite this