Core-shell spheroidal hydrogels produced via charge-driven interfacial complexation

Vincenzo Calabrese; Davide Califano; Marcelo Alves Da Silva; Julien Schmitt; Saffron Jade Bryant; Kazi M. Zakir Hossain; Ana Maria Percebom; Aurora Perez-gramatges; Janet Lesley Scott; Karen J. Edler

doi:10.1021/acsapm.9b01086

Core-shell spheroidal hydrogels produced via charge-driven interfacial complexation

Vincenzo Calabrese
, Davide Califano
, Marcelo Alves Da Silva
, Julien Schmitt
, Saffron Jade Bryant
, Kazi M. Zakir Hossain
, Ana Maria Percebom
, Aurora Perez-gramatges
, Janet Lesley Scott
, Karen J. Edler

Research output: Contribution to journal › Article › peer-review

3 Citations (SciVal)

Abstract

Through charge-driven interfacial complexation, we produced millimetre-sized spheroidal hydrogels (SH) with a core-shell structure allowing long term stability in aqueous media. The SH were fabricated by extruding, drop-wise, a cationic cellulose nanofibril (CCNF) dispersion into an oppositely charged polyacrylic acid (PAA) bath. The SH have a solid-like CCNF-PAA shell, acting as a semi-permeable membrane, and a liquid-like CCNF suspension in the core. Swelling behaviour of the SH was dependent on the osmotic pressure of the ageing media. Swelling could be supressed by increasing the ionic strength of the media as this enhanced interfibrillar interactions and thus strengthened the outer gel membrane. We further validated a potential application of SH as re-usable matrixes for glucose oxidase (GOx) entrapment, where the SH work as “microreactors” from which substrate and product are freely able to migrate, through the SH shell whilst avoiding enzyme leakage.

Original language	English
Pages (from-to)	1213-1221
Number of pages	9
Journal	ACS Applied Polymer Materials
Volume	2
Issue number	3
Early online date	12 Feb 2020
DOIs	https://doi.org/10.1021/acsapm.9b01086
Publication status	Published - 13 Mar 2020

Bibliographical note

Open access has been sorted out now, so the paper is published under a CC-BY licence.

Access to Document

10.1021/acsapm.9b01086Licence: CC BY

https://pubs.acs.org/doi/10.1021/acsapm.9b01086Licence: CC BY

Responsive Pickering Emulsions with High Stability for Slow-Release of Sunscreens and Insecticides
Scott, J. L. (PI) & Edler, K. (CoI)
The Royal Society
1/08/16 → 31/12/18
Project: Research council
New Enzymatically Produced Interpenetrating Starch-Cellulose Gels
Edler, K. (PI) & Scott, J. L. (CoI)
Engineering and Physical Sciences Research Council
6/06/16 → 31/01/21
Project: Research council

Dataset for "Core-shell spheroidal hydrogels produced via charge-driven interfacial complexation"
Calabrese, V. (Creator), Califano, D. (Creator), Alves Da Silva, M. (Creator), Schmitt, J. (Creator), Bryant, S. (Creator), Hossain, K. M. Z. (Creator), Percebom, A. M. (Creator), Gramatges, A. P. (Creator), Scott, J. L. (Creator) & Edler, K. (Creator), University of Bath, 6 Mar 2020
DOI: 10.15125/BATH-00760
Dataset

HR-2 Discovery Hybrid Rheometer
Department of Architecture & Civil Engineering
Facility/equipment: Equipment
Zetasizer
Department of Chemical Engineering
Facility/equipment: Equipment

Cite this

@article{4ad40299f6a0440d9973a9ff73bbfd91,

title = "Core-shell spheroidal hydrogels produced via charge-driven interfacial complexation",

abstract = "Through charge-driven interfacial complexation, we produced millimetre-sized spheroidal hydrogels (SH) with a core-shell structure allowing long term stability in aqueous media. The SH were fabricated by extruding, drop-wise, a cationic cellulose nanofibril (CCNF) dispersion into an oppositely charged polyacrylic acid (PAA) bath. The SH have a solid-like CCNF-PAA shell, acting as a semi-permeable membrane, and a liquid-like CCNF suspension in the core. Swelling behaviour of the SH was dependent on the osmotic pressure of the ageing media. Swelling could be supressed by increasing the ionic strength of the media as this enhanced interfibrillar interactions and thus strengthened the outer gel membrane. We further validated a potential application of SH as re-usable matrixes for glucose oxidase (GOx) entrapment, where the SH work as “microreactors” from which substrate and product are freely able to migrate, through the SH shell whilst avoiding enzyme leakage.",

author = "Vincenzo Calabrese and Davide Califano and \{Da Silva\}, \{Marcelo Alves\} and Julien Schmitt and Bryant, \{Saffron Jade\} and Hossain, \{Kazi M. Zakir\} and Percebom, \{Ana Maria\} and Aurora Perez-gramatges and Scott, \{Janet Lesley\} and Edler, \{Karen J.\}",

note = "Open access has been sorted out now, so the paper is published under a CC-BY licence.",

year = "2020",

month = mar,

day = "13",

doi = "10.1021/acsapm.9b01086",

language = "English",

volume = "2",

pages = "1213--1221",

journal = "ACS Applied Polymer Materials",

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publisher = "American Chemical Society",

number = "3",

}

TY - JOUR

T1 - Core-shell spheroidal hydrogels produced via charge-driven interfacial complexation

AU - Calabrese, Vincenzo

AU - Califano, Davide

AU - Da Silva, Marcelo Alves

AU - Schmitt, Julien

AU - Bryant, Saffron Jade

AU - Hossain, Kazi M. Zakir

AU - Percebom, Ana Maria

AU - Perez-gramatges, Aurora

AU - Scott, Janet Lesley

AU - Edler, Karen J.

N1 - Open access has been sorted out now, so the paper is published under a CC-BY licence.

PY - 2020/3/13

Y1 - 2020/3/13

N2 - Through charge-driven interfacial complexation, we produced millimetre-sized spheroidal hydrogels (SH) with a core-shell structure allowing long term stability in aqueous media. The SH were fabricated by extruding, drop-wise, a cationic cellulose nanofibril (CCNF) dispersion into an oppositely charged polyacrylic acid (PAA) bath. The SH have a solid-like CCNF-PAA shell, acting as a semi-permeable membrane, and a liquid-like CCNF suspension in the core. Swelling behaviour of the SH was dependent on the osmotic pressure of the ageing media. Swelling could be supressed by increasing the ionic strength of the media as this enhanced interfibrillar interactions and thus strengthened the outer gel membrane. We further validated a potential application of SH as re-usable matrixes for glucose oxidase (GOx) entrapment, where the SH work as “microreactors” from which substrate and product are freely able to migrate, through the SH shell whilst avoiding enzyme leakage.

AB - Through charge-driven interfacial complexation, we produced millimetre-sized spheroidal hydrogels (SH) with a core-shell structure allowing long term stability in aqueous media. The SH were fabricated by extruding, drop-wise, a cationic cellulose nanofibril (CCNF) dispersion into an oppositely charged polyacrylic acid (PAA) bath. The SH have a solid-like CCNF-PAA shell, acting as a semi-permeable membrane, and a liquid-like CCNF suspension in the core. Swelling behaviour of the SH was dependent on the osmotic pressure of the ageing media. Swelling could be supressed by increasing the ionic strength of the media as this enhanced interfibrillar interactions and thus strengthened the outer gel membrane. We further validated a potential application of SH as re-usable matrixes for glucose oxidase (GOx) entrapment, where the SH work as “microreactors” from which substrate and product are freely able to migrate, through the SH shell whilst avoiding enzyme leakage.

U2 - 10.1021/acsapm.9b01086

DO - 10.1021/acsapm.9b01086

M3 - Article

SN - 2637-6105

VL - 2

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EP - 1221

JO - ACS Applied Polymer Materials

JF - ACS Applied Polymer Materials

IS - 3

ER -

Core-shell spheroidal hydrogels produced via charge-driven interfacial complexation

Abstract

Bibliographical note

Access to Document

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Projects

Responsive Pickering Emulsions with High Stability for Slow-Release of Sunscreens and Insecticides

New Enzymatically Produced Interpenetrating Starch-Cellulose Gels

Datasets

Dataset for "Core-shell spheroidal hydrogels produced via charge-driven interfacial complexation"

Equipment

HR-2 Discovery Hybrid Rheometer

Zetasizer

Cite this