Copper-catalysed reductive amination of nitriles and organic-group reductions using dimethylamine borane

Dominic Van Der Waals; Alan Pettman; Jonathan M J Williams

doi:10.1039/c4ra11193a

Copper-catalysed reductive amination of nitriles and organic-group reductions using dimethylamine borane

Dominic Van Der Waals, Alan Pettman, Jonathan M J Williams

Pfizer

Research output: Contribution to journal › Article › peer-review

18 Citations (SciVal)

Abstract

A heterogeneous copper catalyst, formed in situ, has been shown to dehydrocouple commercially available amine boranes whilst transferring hydrogen for the reduction of selected organic functional groups in an aqueous medium. The catalytic system has also been shown to promote the reductive amination of aryl nitriles.

Original language	English
Pages (from-to)	51845-51849
Number of pages	5
Journal	RSC Advances
Volume	4
Issue number	94
Early online date	25 Sept 2014
DOIs	https://doi.org/10.1039/c4ra11193a
Publication status	Published - 2014

ASJC Scopus subject areas

General Chemical Engineering
General Chemistry

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10.1039/c4ra11193a

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title = "Copper-catalysed reductive amination of nitriles and organic-group reductions using dimethylamine borane",

abstract = "A heterogeneous copper catalyst, formed in situ, has been shown to dehydrocouple commercially available amine boranes whilst transferring hydrogen for the reduction of selected organic functional groups in an aqueous medium. The catalytic system has also been shown to promote the reductive amination of aryl nitriles.",

author = "{Van Der Waals}, Dominic and Alan Pettman and Williams, {Jonathan M J}",

year = "2014",

doi = "10.1039/c4ra11193a",

language = "English",

volume = "4",

pages = "51845--51849",

journal = "RSC Advances",

issn = "2046-2069",

publisher = "Royal Society of Chemistry",

number = "94",

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T1 - Copper-catalysed reductive amination of nitriles and organic-group reductions using dimethylamine borane

AU - Van Der Waals, Dominic

AU - Pettman, Alan

AU - Williams, Jonathan M J

PY - 2014

Y1 - 2014

N2 - A heterogeneous copper catalyst, formed in situ, has been shown to dehydrocouple commercially available amine boranes whilst transferring hydrogen for the reduction of selected organic functional groups in an aqueous medium. The catalytic system has also been shown to promote the reductive amination of aryl nitriles.

AB - A heterogeneous copper catalyst, formed in situ, has been shown to dehydrocouple commercially available amine boranes whilst transferring hydrogen for the reduction of selected organic functional groups in an aqueous medium. The catalytic system has also been shown to promote the reductive amination of aryl nitriles.

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UR - http://dx.doi.org/10.1039/c4ra11193a

U2 - 10.1039/c4ra11193a

DO - 10.1039/c4ra11193a

M3 - Article

AN - SCOPUS:84908244339

SN - 2046-2069

VL - 4

SP - 51845

EP - 51849

JO - RSC Advances

JF - RSC Advances

IS - 94

ER -

Copper-catalysed reductive amination of nitriles and organic-group reductions using dimethylamine borane

Abstract

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Copper-catalysed reductive amination of nitriles and organic-group reductions using dimethylamine borane

Abstract

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