The amine-functionalised metal-organic framework (MOF) [Zn 4O(bdc-NH 2) 3] (IRMOF-3, bdc-NH 2 = 2-amino-1,4-benzenedicarboxylate) has been post-synthetically modified in a tandem condensation-reduction process into secondary amine-containing MOFs. The degree of modification is enhanced by introduction of methanol, which helps to remove boron-containing side-products from the pores.
Burrows, A. D., & Keenan, L. L. (2012). Conversion of primary amines into secondary amines on a metal–organic framework using a tandem post-synthetic modification. CrystEngComm, 14(12), 4112-4114. https://doi.org/10.1039/c2ce25131k