Controlled clinical trials in cancer pain. How controlled should they be? A qualitative systematic review

R F Bell, T Wisloff, C Eccleston, E Kalso

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

This qualitative systematic review of the clinical methodology used in randomised, controlled trials of oral opioids (morphine, hydromorphone, oxycodone) for cancer pain underlines the difficulties of good pain research in palliative care. The current literature lacks placebo-controlled superiority trials. Recommendations for future research are discussed.
Original languageEnglish
Pages (from-to)1559-1567
Number of pages9
JournalBritish Journal of Cancer
Volume94
Issue number11
DOIs
Publication statusPublished - 2006

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