Continuous power generation from glucose with two different miniature flow-through enzymatic biofuel cells

Hendrik Du Toit, Mirella Di Lorenzo

Research output: Contribution to journalArticle

  • 19 Citations

Abstract

Enzymatic biofuel cells (EBFCs) can generate energy from metabolites present in physiological fluids. They represent an attractive alternative to lithium batteries to power implantable devices, as they work at body temperature, are light and easy-to-miniaturise. To be implantable in blood vessels, EBFCs should not only be made of non-toxic and biocompatible compounds but should also be able to operate in continuous flow-through mode. The EBFC devices reported so far, however, implement carbon-based materials of questionable toxicity and stability, such as carbon nanotubes, and rely on the use of external redox mediators for the electrical connection between the enzyme and the electrode. With this study, we demonstrate for the first time continuous power generation by flow through miniature enzymatic biofuel cells fed with an aerated solution of glucose and no redox mediators. Non-toxic highly porous gold was used as the electrode material and the immobilisation of the enzymes onto the electrodes surface was performed via cost-effective and easy-to-reproduce methodologies. The results presented here are a significant step towards the development of revolutionary implantable medical devices that extract the power they require from metabolites in the body.
LanguageEnglish
Pages199-205
JournalBiosensors and Bioelectronics
Volume69
DOIs
StatusPublished - 15 Jul 2015

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Enzymatic fuel cells
Bioelectric Energy Sources
Power generation
Glucose
Biosensing Techniques
Metabolites
Equipment and Supplies
Electrodes
Oxidation-Reduction
Enzymes
Carbon Nanotubes
Lithium batteries
Blood vessels
Body Temperature
Lithium
Immobilization
Gold
Blood Vessels
Toxicity
Carbon nanotubes

Keywords

  • Enzymatic fuel cell, glucose oxidase, laccase, flow through, highly porous gold

Cite this

Continuous power generation from glucose with two different miniature flow-through enzymatic biofuel cells. / Du Toit, Hendrik; Di Lorenzo, Mirella.

In: Biosensors and Bioelectronics, Vol. 69, 15.07.2015, p. 199-205.

Research output: Contribution to journalArticle

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