Continuities in maternal substance use from early adolescence to parenthood: findings from the intergenerational cohort consortium

Kimberly C Thomson; Christopher J Greenwood; Primrose Letcher; Elizabeth A Spry; Jacqui A Macdonald; Helena M McAnally; Lindsey A Hines; George J Youssef; Jennifer E McIntosh; Delyse Hutchinson; Robert J Hancox; George C Patton; Craig A Olsson

doi:10.1017/S0033291721003925

Continuities in maternal substance use from early adolescence to parenthood: findings from the intergenerational cohort consortium

Kimberly C Thomson, Christopher J Greenwood, Primrose Letcher, Elizabeth A Spry, Jacqui A Macdonald, Helena M McAnally, Lindsey A Hines, George J Youssef, Jennifer E McIntosh, Delyse Hutchinson, Robert J Hancox, George C Patton, Craig A Olsson

Department of Psychology

Research output: Contribution to journal › Article › peer-review

5 Citations (SciVal)

Abstract

Background: This study assessed the extent to which women's preconception binge drinking, tobacco use and cannabis use, reported prospectively in adolescence and young adulthood, predicted use of these substances during pregnancy and at 1 year postpartum.

Methods: Data were pooled from two intergenerational cohort studies: the Australian Temperament Project Generation 3 Study (395 mothers, 691 pregnancies) and the Victorian Intergenerational Health Cohort Study (398 mothers, 609 pregnancies). Alcohol, tobacco and cannabis use were assessed in adolescence (13-18 years), young adulthood (19-29 years) and at ages 29-35 years for those transitioning to parenthood. Exposures were weekly or more frequent preconception binge drinking (5 + drinks in one session), tobacco use and cannabis use. Outcomes were any alcohol, tobacco and cannabis use prior to awareness of the pregnancy, after awareness of pregnancy (up to and including the third trimester pregnancy) and at 1 year postpartum.

Results: Frequent preconception binge drinking, tobacco use and cannabis use across both adolescence and young adulthood were strong predictors of continued use post-conception, before and after awareness of the pregnancy and at 1 year postpartum. Substance use limited to young adulthood also predicted continued use post-conception.

Conclusions: Persistent alcohol, tobacco use and cannabis use that starts in adolescence has a strong continuity into parenthood. Reducing substance use in the perinatal period requires action well before pregnancy, commencing in adolescence and continuing into the years before conception and throughout the perinatal period.

Original language	English
Pages (from-to)	2136-2145
Number of pages	10
Journal	Psychological Medicine
Volume	53
Issue number	5
Early online date	8 Oct 2021
DOIs	https://doi.org/10.1017/S0033291721003925
Publication status	Published - 8 Apr 2023

Funding

Funding for this work was supported by grants for CAO from the Australian Research Council [DP130101459; DP160103160; DP180102447] and the National Health and Medical Research Council of Australia (NHMRC) [APP1082406]. GCP was supported by the NHMRC [APP1117873]. KCT was supported by funding from the Canadian Institutes of Health Research [MFE158141] and Michael Smith Foundation for Health Research [RT-2020-0550]. Additionally, this work was supported by the NHMRC (APP1008273, APP1063091, APP437015), Australian Rotary Health, Colonial Foundation, Perpetual Trustees, Financial Markets Foundation for Children (Australia), Royal Children’s Hospital Foundation and the Murdoch Children’s Research Institute. Research at the Murdoch Children’s Research Institute is supported by the Victorian Government’s Operational Infrastructure Program.

Keywords

Adolescence
cohort studies
intergenerational
longitudinal data analysis
substance use

ASJC Scopus subject areas

Psychiatry and Mental health
Applied Psychology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1017/S0033291721003925

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Thomson, K. C., Greenwood, C. J., Letcher, P., Spry, E. A., Macdonald, J. A., McAnally, H. M., Hines, L. A., Youssef, G. J., McIntosh, J. E., Hutchinson, D., Hancox, R. J., Patton, G. C., & Olsson, C. A. (2023). Continuities in maternal substance use from early adolescence to parenthood: findings from the intergenerational cohort consortium. Psychological Medicine, 53(5), 2136-2145. https://doi.org/10.1017/S0033291721003925

Thomson, KC, Greenwood, CJ, Letcher, P, Spry, EA, Macdonald, JA, McAnally, HM, Hines, LA, Youssef, GJ, McIntosh, JE, Hutchinson, D, Hancox, RJ, Patton, GC & Olsson, CA 2023, 'Continuities in maternal substance use from early adolescence to parenthood: findings from the intergenerational cohort consortium', Psychological Medicine, vol. 53, no. 5, pp. 2136-2145. https://doi.org/10.1017/S0033291721003925

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abstract = "Background: This study assessed the extent to which women's preconception binge drinking, tobacco use and cannabis use, reported prospectively in adolescence and young adulthood, predicted use of these substances during pregnancy and at 1 year postpartum.Methods: Data were pooled from two intergenerational cohort studies: the Australian Temperament Project Generation 3 Study (395 mothers, 691 pregnancies) and the Victorian Intergenerational Health Cohort Study (398 mothers, 609 pregnancies). Alcohol, tobacco and cannabis use were assessed in adolescence (13-18 years), young adulthood (19-29 years) and at ages 29-35 years for those transitioning to parenthood. Exposures were weekly or more frequent preconception binge drinking (5 + drinks in one session), tobacco use and cannabis use. Outcomes were any alcohol, tobacco and cannabis use prior to awareness of the pregnancy, after awareness of pregnancy (up to and including the third trimester pregnancy) and at 1 year postpartum.Results: Frequent preconception binge drinking, tobacco use and cannabis use across both adolescence and young adulthood were strong predictors of continued use post-conception, before and after awareness of the pregnancy and at 1 year postpartum. Substance use limited to young adulthood also predicted continued use post-conception.Conclusions: Persistent alcohol, tobacco use and cannabis use that starts in adolescence has a strong continuity into parenthood. Reducing substance use in the perinatal period requires action well before pregnancy, commencing in adolescence and continuing into the years before conception and throughout the perinatal period.",

keywords = "Adolescence, cohort studies, intergenerational, longitudinal data analysis, substance use",

author = "Thomson, {Kimberly C} and Greenwood, {Christopher J} and Primrose Letcher and Spry, {Elizabeth A} and Macdonald, {Jacqui A} and McAnally, {Helena M} and Hines, {Lindsey A} and Youssef, {George J} and McIntosh, {Jennifer E} and Delyse Hutchinson and Hancox, {Robert J} and Patton, {George C} and Olsson, {Craig A}",

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AU - Greenwood, Christopher J

AU - Letcher, Primrose

AU - Spry, Elizabeth A

AU - Macdonald, Jacqui A

AU - McAnally, Helena M

AU - Hines, Lindsey A

AU - Youssef, George J

AU - McIntosh, Jennifer E

AU - Hutchinson, Delyse

AU - Hancox, Robert J

AU - Patton, George C

AU - Olsson, Craig A

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N2 - Background: This study assessed the extent to which women's preconception binge drinking, tobacco use and cannabis use, reported prospectively in adolescence and young adulthood, predicted use of these substances during pregnancy and at 1 year postpartum.Methods: Data were pooled from two intergenerational cohort studies: the Australian Temperament Project Generation 3 Study (395 mothers, 691 pregnancies) and the Victorian Intergenerational Health Cohort Study (398 mothers, 609 pregnancies). Alcohol, tobacco and cannabis use were assessed in adolescence (13-18 years), young adulthood (19-29 years) and at ages 29-35 years for those transitioning to parenthood. Exposures were weekly or more frequent preconception binge drinking (5 + drinks in one session), tobacco use and cannabis use. Outcomes were any alcohol, tobacco and cannabis use prior to awareness of the pregnancy, after awareness of pregnancy (up to and including the third trimester pregnancy) and at 1 year postpartum.Results: Frequent preconception binge drinking, tobacco use and cannabis use across both adolescence and young adulthood were strong predictors of continued use post-conception, before and after awareness of the pregnancy and at 1 year postpartum. Substance use limited to young adulthood also predicted continued use post-conception.Conclusions: Persistent alcohol, tobacco use and cannabis use that starts in adolescence has a strong continuity into parenthood. Reducing substance use in the perinatal period requires action well before pregnancy, commencing in adolescence and continuing into the years before conception and throughout the perinatal period.

AB - Background: This study assessed the extent to which women's preconception binge drinking, tobacco use and cannabis use, reported prospectively in adolescence and young adulthood, predicted use of these substances during pregnancy and at 1 year postpartum.Methods: Data were pooled from two intergenerational cohort studies: the Australian Temperament Project Generation 3 Study (395 mothers, 691 pregnancies) and the Victorian Intergenerational Health Cohort Study (398 mothers, 609 pregnancies). Alcohol, tobacco and cannabis use were assessed in adolescence (13-18 years), young adulthood (19-29 years) and at ages 29-35 years for those transitioning to parenthood. Exposures were weekly or more frequent preconception binge drinking (5 + drinks in one session), tobacco use and cannabis use. Outcomes were any alcohol, tobacco and cannabis use prior to awareness of the pregnancy, after awareness of pregnancy (up to and including the third trimester pregnancy) and at 1 year postpartum.Results: Frequent preconception binge drinking, tobacco use and cannabis use across both adolescence and young adulthood were strong predictors of continued use post-conception, before and after awareness of the pregnancy and at 1 year postpartum. Substance use limited to young adulthood also predicted continued use post-conception.Conclusions: Persistent alcohol, tobacco use and cannabis use that starts in adolescence has a strong continuity into parenthood. Reducing substance use in the perinatal period requires action well before pregnancy, commencing in adolescence and continuing into the years before conception and throughout the perinatal period.

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KW - cohort studies

KW - intergenerational

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Continuities in maternal substance use from early adolescence to parenthood: findings from the intergenerational cohort consortium

Abstract

Funding

Keywords

ASJC Scopus subject areas

UN SDGs

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