Construction of Bio-Piezoelectric Platforms: From Structures and Synthesis to Applications

Qianqian Xu, Xinyu Gao, Senfeng Zhao, You Nian Liu, Dou Zhang, Kechao Zhou, Hamideh Khanbareh, Wansong Chen, Yan Zhang, Chris Bowen

Research output: Contribution to journalReview articlepeer-review

133 Citations (SciVal)


Piezoelectric materials, with their unique ability for mechanical-electrical energy conversion, have been widely applied in important fields such as sensing, energy harvesting, wastewater treatment, and catalysis. In recent years, advances in material synthesis and engineering have provided new opportunities for the development of bio-piezoelectric materials with excellent biocompatibility and piezoelectric performance. Bio-piezoelectric materials have attracted interdisciplinary research interest due to recent insights on the impact of piezoelectricity on biological systems and their versatile biomedical applications. This review therefore introduces the development of bio-piezoelectric platforms from a broad perspective and highlights their design and engineering strategies. State-of-the-art biomedical applications in both biosensing and disease treatment will be systematically outlined. The relationships between the properties, structure, and biomedical performance of the bio-piezoelectric materials are examined to provide a deep understanding of the working mechanisms in a physiological environment. Finally, the development trends and challenges are discussed, with the aim to provide new insights for the design and construction of future bio-piezoelectric materials.

Original languageEnglish
Article number2008452
JournalAdvanced Materials
Issue number27
Early online date25 May 2021
Publication statusPublished - 8 Jul 2021


  • biomedicine
  • biosensing
  • disease treatment
  • piezoelectric materials

ASJC Scopus subject areas

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering


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