Concise synthesis of taxol A-ring components: Remote diastereoselective additions of alkenyl lithiums to aldehydes

C. Frost; P. Linnane; P. Magnus; M. Spyvee

doi:10.1016/S0040-4039(96)02159-4

Concise synthesis of taxol A-ring components: Remote diastereoselective additions of alkenyl lithiums to aldehydes

C. Frost
, P. Linnane
, P. Magnus
, M. Spyvee

University of Texas

Research output: Contribution to journal › Article › peer-review

19 Citations (SciVal)

Abstract

The acid chloride 6 provides access to 7 (R,S and S,S) which upon bromine-lithium exchange undergoes remarkably highly diastereoselective additions to aldehydes; 7 is also readily elaborated into the acetal 10.

Original language	English
Pages (from-to)	9139-9142
Number of pages	4
Journal	Tetrahedron Letters
Volume	37
Issue number	51
DOIs	https://doi.org/10.1016/S0040-4039(96)02159-4
Publication status	Published - 16 Dec 1996

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@article{f0c92245606141f38d9241d3f6e701a2,

title = "Concise synthesis of taxol A-ring components: Remote diastereoselective additions of alkenyl lithiums to aldehydes",

abstract = "The acid chloride 6 provides access to 7 (R,S and S,S) which upon bromine-lithium exchange undergoes remarkably highly diastereoselective additions to aldehydes; 7 is also readily elaborated into the acetal 10.",

author = "C. Frost and P. Linnane and P. Magnus and M. Spyvee",

year = "1996",

month = dec,

day = "16",

doi = "10.1016/S0040-4039(96)02159-4",

language = "English",

volume = "37",

pages = "9139--9142",

journal = "Tetrahedron Letters",

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TY - JOUR

T1 - Concise synthesis of taxol A-ring components

T2 - Remote diastereoselective additions of alkenyl lithiums to aldehydes

AU - Frost, C.

AU - Linnane, P.

AU - Magnus, P.

AU - Spyvee, M.

PY - 1996/12/16

Y1 - 1996/12/16

N2 - The acid chloride 6 provides access to 7 (R,S and S,S) which upon bromine-lithium exchange undergoes remarkably highly diastereoselective additions to aldehydes; 7 is also readily elaborated into the acetal 10.

AB - The acid chloride 6 provides access to 7 (R,S and S,S) which upon bromine-lithium exchange undergoes remarkably highly diastereoselective additions to aldehydes; 7 is also readily elaborated into the acetal 10.

UR - https://www.scopus.com/pages/publications/0030590991

UR - http://dx.doi.org/10.1016/S0040-4039(96)02159-4

U2 - 10.1016/S0040-4039(96)02159-4

DO - 10.1016/S0040-4039(96)02159-4

M3 - Article

AN - SCOPUS:0030590991

SN - 0040-4039

VL - 37

SP - 9139

EP - 9142

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 51

ER -

Concise synthesis of taxol A-ring components: Remote diastereoselective additions of alkenyl lithiums to aldehydes

Abstract

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