Compound Class 18: 1,1-Diacyloxy Compounds

Laura H. Smith, Susannah C. Coote, David J. Procter

Research output: Chapter or section in a book/report/conference proceedingChapter or section


1,1-Diacyloxy compounds can be accessed from a variety of starting materials including aldehydes, ketones, and O/O, O/Hal, and Hal/Hal acetals under a variety of reaction conditions. This product class encompasses Meldrum’s acid, several natural products, and acyloxy ester prodrugs; in addition, acyl acetals are useful protecting groups for aldehydes and can be cleaved orthogonally to alkyl acetals.
Original languageEnglish
Title of host publicationScience of Synthesis
EditorsK. Ishihara, D. J. Proctor, E. Schaumann
Place of PublicationStuttgart, Germany
PublisherGeorg Thieme Verlag
ISBN (Electronic)9783131843814
ISBN (Print)9783131541611
Publication statusPublished - 31 Mar 2010


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