Comparison studies of applied pressure and concentration gradient driving forces in ceramic nano-filtration membrane for the production of intravenous salt solution

In this study, the boundary-resistance layer model and soln.-diffusion model were used to investigate the applied driving pressure force technique and the concn. driving force technique, resp., for the prodn. of i.v. drip soln. A 5 kD monolithic membrane coated with Al2O3 and TiO and NaCl aq. soln. as the feed soln. was used. The results show that the boundary-resistance layer model diffusivity coeff., D = 1.8*10-9 m2 sec-1 and the mass transfer coeff., k = 1.19-10-4 m sec-1 which were both slightly higher than the soln.-diffusion model. Applying Fick's law for the soln. diffusion model, the calcd. operating pressure inside the lumen was 15 kPa. Clearly, the findings suggested that the boundary-resistance layer model should be chosen for the prodn. of pure and sterile i.v. salt soln. as it provided higher diffusivity and mass transfer coeff. than the soln.-diffusion model. [on SciFinder (R)]