Comparison studies of applied pressure and concentration gradient driving forces in ceramic nano-filtration membrane for the production of intravenous salt solution

Rosalam Sarbatly, Duduku Krishnaiah, Richard England, Sariah Abang, Jeanette Jeffery

Research output: Contribution to journalArticlepeer-review

Abstract

In this study, the boundary-resistance layer model and soln.-diffusion model were used to investigate the applied driving pressure force technique and the concn. driving force technique, resp., for the prodn. of i.v. drip soln. A 5 kD monolithic membrane coated with Al2O3 and TiO and NaCl aq. soln. as the feed soln. was used. The results show that the boundary-resistance layer model diffusivity coeff., D = 1.8*10-9 m2 sec-1 and the mass transfer coeff., k = 1.19-10-4 m sec-1 which were both slightly higher than the soln.-diffusion model. Applying Fick's law for the soln. diffusion model, the calcd. operating pressure inside the lumen was 15 kPa. Clearly, the findings suggested that the boundary-resistance layer model should be chosen for the prodn. of pure and sterile i.v. salt soln. as it provided higher diffusivity and mass transfer coeff. than the soln.-diffusion model. [on SciFinder (R)]
Original languageEnglish
Pages (from-to)2069-2075
Number of pages7
JournalJournal of Applied Sciences
Volume7
Issue number15
Publication statusPublished - 2007

Keywords

  • intravenous salt soln nanofiltration ceramic membrane sterilization
  • mass transfer coeff. and osmotic pressure than soln. diffusion model suggesting usefulness of former for prodn. of pure and sterile i.v. salt soln.)
  • Permeability (boundary resistance layer model showed higher diffusivity and mass transfer coeff. through ceramic nanofiltration membrane than soln. diffusion model suggesting usefulness of former for prodn. of i.v. salt soln.)
  • Osmotic pressure (boundary resistance layer model showed higher diffusivity
  • Sterilization and Disinfection (applied pressure driving force technique was useful for prodn. of pure and sterile i.v. salt soln. compared to concn. driving force technique)
  • Filtration (nanofiltration
  • boundary resistance layer model showed higher diffusivity and mass transfer coeff. through ceramic nanofiltration membrane than soln. diffusion model suggesting usefulness of former for prodn. of i.v. salt soln.)
  • Ceramic membranes
  • Diffusion
  • Mass transfer

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