Combining Constrained Heptapeptide Cassettes With Computational Design to Create Coiled-coil Targeting Helical Peptides

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  A High Throughput Screen to Derive Functional Antagonists of Transcription Factor Cancer Targets.

  Mason, J. (PI)

  Cancer Research UK

  1/12/18 → 31/08/21

  Project: UK charity

  • Peptide 100%
  • Peptide Library 48%
  • Carcinogenesis 43%
  • Transcription 39%
  • AP-1 Transcription Factor 39%

• A Generalised Approach to Derive Functionally Active Peptide Inhibitors of Transcription Factor Activity

  Mason, J. (PI)

  Biotechnology and Biological Sciences Research Council

  1/10/18 → 30/06/22

  Project: Research council

  • Peptide 100%
  • Transcription Factors 60%
  • AP-1 Transcription Factor 59%
  • Peptides 48%
  • Transcription Factor AP 1 34%

• Establishing an Approach for the Selection and Design of Secondary Structure Mimetics to Antagonise Protein-Protein Interactions

  Mason, J. (PI)

  EPSRC

  1/05/15 → 31/12/18

  Project: Research council

  • Peptide 100%
  • Coiled Coil 34%
  • Protein-Protein Interaction 32%
  • Basic Leucine Zipper Transcription Factor 32%
  • AP-1 Transcription Factor 28%