Combining Constrained Heptapeptide Cassettes With Computational Design to Create Coiled-coil Targeting Helical Peptides

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  A Generalised Approach to Derive Functionally Active Peptide Inhibitors of Transcription Factor Activity

  Mason, J. (PI)

  Biotechnology and Biological Sciences Research Council

  1/10/18 → 30/06/22

  Project: Research council

  • AP-1 Transcription Factor 100%
  • Transcription Factors 80%
  • Peptide Library 59%
  • Transcription 51%
  • Signal Transduction 36%

• Establishing an Approach for the Selection and Design of Secondary Structure Mimetics to Antagonise Protein-Protein Interactions

  Mason, J. (PI)

  Engineering and Physical Sciences Research Council

  1/05/15 → 31/12/18

  Project: Research council

  • Coiled Coil 100%
  • Protein-Protein Interaction 92%
  • AP-1 Transcription Factor 86%
  • Basic Leucine Zipper Transcription Factor 74%
  • Peptide Library 74%