"Click-fluors": Modular fluorescent saccharide sensors based on a 1,2,3-triazole ring

D K Scrafton, J E Taylor, M F Mahon, J S Fossey, T D James

Research output: Contribution to journalArticle

80 Citations (Scopus)

Abstract

A carbohydrate sensing "click-fluor" is reported which displays a nontypical binding preference with sample saccharides. That a fluorescent sensor is generated as a result of triazole formation (click reaction), rather than simply bringing the sensor and reporter units together via a triazole linkage, and the potential applicability of the wide range of easily accessible acetylene units means a simple strategy for the development of modular fluorescent sensor arrays for rapid screening of target saccharides will be available.
Original languageEnglish
Pages (from-to)2871-2874
Number of pages4
JournalJournal of Organic Chemistry
Volume73
Issue number7
Early online date13 Mar 2008
DOIs
Publication statusPublished - 4 Apr 2008

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Triazoles
Acetylene
Sensors
Sensor arrays
Screening
Carbohydrates

Cite this

"Click-fluors": Modular fluorescent saccharide sensors based on a 1,2,3-triazole ring. / Scrafton, D K; Taylor, J E; Mahon, M F; Fossey, J S; James, T D.

In: Journal of Organic Chemistry, Vol. 73, No. 7, 04.04.2008, p. 2871-2874.

Research output: Contribution to journalArticle

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