The cholesterol moiety is the perfect host. The environment it creates changes to accomodate each new guest. Cholesteric liquid crystals change colour. Cholesteric gels have different phase transition temperatures. Cholesteric LB films change the area they cover.
James, T. D., Kawabata, H., Ludwig, R., Murata, K., & Shinkai, S. (1995). Cholesterol as a versatile platform for chiral recognition. Tetrahedron, 51(25), 555-566. https://doi.org/10.1016/0040-4020(94)00915-H