Chiral desymmetrisation of myo-inositol 1,3,5-orthobenzoate gives rapid access to precursors for second messenger analogues

Andrew M. Riley; H. Yasmin Godage; Mary F. Mahon; Barry V. L. Potter

doi:10.1016/j.tetasy.2005.12.008

Chiral desymmetrisation of myo-inositol 1,3,5-orthobenzoate gives rapid access to precursors for second messenger analogues

Andrew M. Riley, H. Yasmin Godage, Mary F. Mahon, Barry V. L. Potter

Research output: Contribution to journal › Article › peer-review

21 Citations (SciVal)

Abstract

Chiral desymmetrisation of myo-inositol 1,3,5-orthobenzoate via the formation of diastereoisomeric bis[(1S)-(-)-camphanate] esters provides a convenient and fast route to precursors for biologically important inositol phosphates and lipids, and to synthetic analogues and probes modified at O-1 or O-3 of the inositol ring.

Original language	English
Pages (from-to)	171-174
Number of pages	4
Journal	Tetrahedron: Asymmetry
Volume	17
Issue number	2
DOIs	https://doi.org/10.1016/j.tetasy.2005.12.008
Publication status	Published - 2006

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10.1016/j.tetasy.2005.12.008

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title = "Chiral desymmetrisation of myo-inositol 1,3,5-orthobenzoate gives rapid access to precursors for second messenger analogues",

abstract = "Chiral desymmetrisation of myo-inositol 1,3,5-orthobenzoate via the formation of diastereoisomeric bis[(1S)-(-)-camphanate] esters provides a convenient and fast route to precursors for biologically important inositol phosphates and lipids, and to synthetic analogues and probes modified at O-1 or O-3 of the inositol ring.",

author = "Riley, {Andrew M.} and Godage, {H. Yasmin} and Mahon, {Mary F.} and Potter, {Barry V. L.}",

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AU - Riley, Andrew M.

AU - Godage, H. Yasmin

AU - Mahon, Mary F.

AU - Potter, Barry V. L.

PY - 2006

Y1 - 2006

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AB - Chiral desymmetrisation of myo-inositol 1,3,5-orthobenzoate via the formation of diastereoisomeric bis[(1S)-(-)-camphanate] esters provides a convenient and fast route to precursors for biologically important inositol phosphates and lipids, and to synthetic analogues and probes modified at O-1 or O-3 of the inositol ring.

UR - http://dx.doi.org/10.1016/j.tetasy.2005.12.008

U2 - 10.1016/j.tetasy.2005.12.008

DO - 10.1016/j.tetasy.2005.12.008

M3 - Article

SN - 0957-4166

VL - 17

SP - 171

EP - 174

JO - Tetrahedron: Asymmetry

JF - Tetrahedron: Asymmetry

IS - 2

ER -

Chiral desymmetrisation of myo-inositol 1,3,5-orthobenzoate gives rapid access to precursors for second messenger analogues

Abstract

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