Chiral desymmetrisation of myo-inositol 1,3,5-orthobenzoate gives rapid access to precursors for second messenger analogues

Andrew M. Riley, H. Yasmin Godage, Mary F. Mahon, Barry V. L. Potter

Research output: Contribution to journalArticlepeer-review

20 Citations (Scopus)

Abstract

Chiral desymmetrisation of myo-inositol 1,3,5-orthobenzoate via the formation of diastereoisomeric bis[(1S)-(-)-camphanate] esters provides a convenient and fast route to precursors for biologically important inositol phosphates and lipids, and to synthetic analogues and probes modified at O-1 or O-3 of the inositol ring.
Original languageEnglish
Pages (from-to)171-174
Number of pages4
JournalTetrahedron: Asymmetry
Volume17
Issue number2
DOIs
Publication statusPublished - 2006

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