A novel fluorescence response to enantiomeric analytes was observed for binol–bisboronic acid sensors (R- or S-1): One enantiomer of the analyte enhances and the other enantiomer diminishes the fluorescence of 1. So, the fluorescence intensity of R-1 was enhanced by D-tartaric acid and diminished by L-tartaric acid (see scheme). These changes are mirrored by the S sensor.
Zhao, J. Z., Fyles, T. M., & James, T. D. (2004). Chiral binol-bisboronic acid as fluorescence sensor for sugar acids. Angewandte Chemie-International Edition, 43(26), 3461-3464. https://doi.org/10.1002/anie.200454033