Characterization of a membrane binding loop leads to engineering botulinum neurotoxin B with improved therapeutic efficacy

Linxiang Yin; Geoffrey Masuyer; Sicai Zhang; Jie Zhang; Shin-Ichiro Miyashita; David Burgin; Laura Lovelock; Shu-Fen Coker; Tian-min Fu; Pal Stenmark; Min Dong

doi:10.1371/journal.pbio.3000618

Characterization of a membrane binding loop leads to engineering botulinum neurotoxin B with improved therapeutic efficacy

Linxiang Yin, Geoffrey Masuyer, Sicai Zhang, Jie Zhang, Shin-Ichiro Miyashita, David Burgin, Laura Lovelock, Shu-Fen Coker, Tian-min Fu, Pal Stenmark, Min Dong

Department of Pharmacy & Pharmacology

Research output: Contribution to journal › Article

Original language	English
Article number	E3000618
Journal	PLoS Biology
Volume	18
Issue number	3
DOIs	https://doi.org/10.1371/journal.pbio.3000618
Publication status	Published - 17 Mar 2020

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10.1371/journal.pbio.3000618Licence: CC BY

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Yin, L., Masuyer, G., Zhang, S., Zhang, J., Miyashita, S-I., Burgin, D., Lovelock, L., Coker, S-F., Fu, T., Stenmark, P., & Dong, M. (2020). Characterization of a membrane binding loop leads to engineering botulinum neurotoxin B with improved therapeutic efficacy. PLoS Biology, 18(3), [E3000618]. https://doi.org/10.1371/journal.pbio.3000618

Characterization of a membrane binding loop leads to engineering botulinum neurotoxin B with improved therapeutic efficacy. / Yin, Linxiang; Masuyer, Geoffrey; Zhang, Sicai; Zhang, Jie; Miyashita, Shin-Ichiro; Burgin, David; Lovelock, Laura; Coker, Shu-Fen; Fu, Tian-min; Stenmark, Pal; Dong, Min.

In: PLoS Biology, Vol. 18, No. 3, E3000618, 17.03.2020.

Research output: Contribution to journal › Article

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