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Centrally acting antihypertensives and alpha-blockers in people at risk of falls: therapeutic dilemmas—a clinical review

  • University of Bristol
  • Royal United Hospitals Bath NHS Foundation Trust
  • Pharmacy Department
  • Plymouth Hospitals NHS Foundation Trust

Research output: Contribution to journalArticlepeer-review

9   Link opens in a new tab Citations (SciVal)

Abstract

Purpose: To summarise the evidence for deprescribing alpha-blockers and centrally acting antihypertensives in older people at risk of falls and to assist clinicians in deciding how to safely de-prescribe these agents. Findings: Alpha-blockers and centrally acting antihypertensives are no longer recommended for the treatment of hypertension unless all other agents are contraindicated or not tolerated. Multiple tools identify these agents as potentially inappropriate and recommend deprescribing. A number of protocols have been developed to safely guide deprescribing. Message: Safer antihypertensives are available that are associated with less adverse effects. Decision aids such as STOPPFalls can assist de-prescribing.

Original languageEnglish
Pages (from-to)675-682
Number of pages8
JournalEuropean Geriatric Medicine
Volume14
Issue number4
Early online date12 Jul 2023
DOIs
Publication statusPublished - 31 Aug 2023

Bibliographical note

Funding: No funding was received for conducting this study.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Deprescribing
  • Falls
  • Geriatric
  • Hypertension

ASJC Scopus subject areas

  • Gerontology
  • Geriatrics and Gerontology

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