Abstract
Drosophila melanogaster is a widely used model for the characterization of blood cell development and function, with an array of protocols for the manipulation and visualization of fixed or live cells in vitro or in vivo. Researchers have deployed these techniques to reveal Drosophila hemocytes as a remarkably versatile cell type that engulfs apoptotic corpses; neutralizes invading parasites; seals epithelial wounds; and deposits extracellular matrix proteins. In this review, we will discuss the key features of Drosophila hemocyte development and function, and identify similarities with vertebrate counterparts.
| Original language | English |
|---|---|
| Pages (from-to) | 95-101 |
| Journal | Developmental and Comparative Immunology |
| Volume | 58 |
| Early online date | 31 Dec 2015 |
| DOIs | |
| Publication status | Published - 27 Feb 2016 |
Funding
The research performed in the lab of EF is supported by a grant from the Canadian Institutes of Health Research (MOP 77746).
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