Abstract
We report the synthesis and characterisation of new, highly fluorescent, zinc complexes of bis(thiosemicarbazone) ligands incorporating extended aromatic backbones which are cytotoxic at levels comparable to cisplatin; cellular fluorescence imaging studies suggest these cause cell death by disruption of mitochondria.
Original language | English |
---|---|
Pages (from-to) | 2107-2110 |
Number of pages | 4 |
Journal | Dalton Transactions |
Volume | 2008 |
Issue number | 16 |
Early online date | 18 Mar 2008 |
DOIs | |
Publication status | Published - 28 Apr 2008 |