Catalytic SNAr of unactivated aryl chlorides

James W. Walton; Jonathan M J Williams

doi:10.1039/c4cc07116f

Catalytic S_NAr of unactivated aryl chlorides

James W. Walton
, Jonathan M J Williams

Durham University

Research output: Contribution to journal › Article › peer-review

45 Citations (SciVal)

Abstract

We present nucleophilic aromatic substitution of unsubstituted aryl chlorides via a mechanism that is catalytic in [CpRu(p-cymene)]PF₆ and involves a Ru(η⁶-arylchloride) intermediate. From the spectroscopic evidence we infer that arene exchange is the rate limiting step in this process and develop several new Ru(ii) complexes that lower the activation barrier to arene exchange.

Original language	English
Pages (from-to)	2786-2789
Number of pages	4
Journal	Chemical Communications
Volume	51
Issue number	14
Early online date	6 Oct 2014
DOIs	https://doi.org/10.1039/c4cc07116f
Publication status	Published - 18 Feb 2015

Access to Document

10.1039/c4cc07116f

Cite this

@article{2a2f5ce9d8234e5693031a69d19e644d,

title = "Catalytic SNAr of unactivated aryl chlorides",

abstract = "We present nucleophilic aromatic substitution of unsubstituted aryl chlorides via a mechanism that is catalytic in [CpRu(p-cymene)]PF6 and involves a Ru(η6-arylchloride) intermediate. From the spectroscopic evidence we infer that arene exchange is the rate limiting step in this process and develop several new Ru(ii) complexes that lower the activation barrier to arene exchange.",

author = "Walton, \{James W.\} and Williams, \{Jonathan M J\}",

year = "2015",

month = feb,

day = "18",

doi = "10.1039/c4cc07116f",

language = "English",

volume = "51",

pages = "2786--2789",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "14",

}

TY - JOUR

T1 - Catalytic SNAr of unactivated aryl chlorides

AU - Walton, James W.

AU - Williams, Jonathan M J

PY - 2015/2/18

Y1 - 2015/2/18

N2 - We present nucleophilic aromatic substitution of unsubstituted aryl chlorides via a mechanism that is catalytic in [CpRu(p-cymene)]PF6 and involves a Ru(η6-arylchloride) intermediate. From the spectroscopic evidence we infer that arene exchange is the rate limiting step in this process and develop several new Ru(ii) complexes that lower the activation barrier to arene exchange.

AB - We present nucleophilic aromatic substitution of unsubstituted aryl chlorides via a mechanism that is catalytic in [CpRu(p-cymene)]PF6 and involves a Ru(η6-arylchloride) intermediate. From the spectroscopic evidence we infer that arene exchange is the rate limiting step in this process and develop several new Ru(ii) complexes that lower the activation barrier to arene exchange.

UR - https://www.scopus.com/pages/publications/84922359927

UR - http://dx.doi.org/10.1039/c4cc07116f

U2 - 10.1039/c4cc07116f

DO - 10.1039/c4cc07116f

M3 - Article

AN - SCOPUS:84922359927

SN - 1359-7345

VL - 51

SP - 2786

EP - 2789

JO - Chemical Communications

JF - Chemical Communications

IS - 14

ER -

Catalytic S_NAr of unactivated aryl chlorides

Abstract

Access to Document

Other files and links

Fingerprint

Dream Fellowship

Cite this

Catalytic SNAr of unactivated aryl chlorides

Abstract

Access to Document

Other files and links

Fingerprint

Projects

Dream Fellowship

Cite this

Catalytic S_NAr of unactivated aryl chlorides