Catalytic SNAr of unactivated aryl chlorides

James W. Walton, Jonathan M J Williams

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

We present nucleophilic aromatic substitution of unsubstituted aryl chlorides via a mechanism that is catalytic in [CpRu(p-cymene)]PF6 and involves a Ru(η6-arylchloride) intermediate. From the spectroscopic evidence we infer that arene exchange is the rate limiting step in this process and develop several new Ru(ii) complexes that lower the activation barrier to arene exchange.

Original languageEnglish
Pages (from-to)2786-2789
Number of pages4
JournalChemical Communications
Volume51
Issue number14
Early online date6 Oct 2014
DOIs
Publication statusPublished - 18 Feb 2015

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Chlorides
Ion exchange
Substitution reactions
Chemical activation
4-cymene

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Catalytic SNAr of unactivated aryl chlorides. / Walton, James W.; Williams, Jonathan M J.

In: Chemical Communications, Vol. 51, No. 14, 18.02.2015, p. 2786-2789.

Research output: Contribution to journalArticle

Walton, JW & Williams, JMJ 2015, 'Catalytic SNAr of unactivated aryl chlorides', Chemical Communications, vol. 51, no. 14, pp. 2786-2789. https://doi.org/10.1039/c4cc07116f
Walton, James W. ; Williams, Jonathan M J. / Catalytic SNAr of unactivated aryl chlorides. In: Chemical Communications. 2015 ; Vol. 51, No. 14. pp. 2786-2789.
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