Abstract
A catalytic meta-selective C–H functionalization of 2-phenylpyridines using a range of tertiary halides is described. The protocol is simple to perform and uses commercially available reagents to construct challenging quaternary carbon centres in a regioselective manner. Preliminary studies suggest the C–H functionalization proceeds through a radical process directed via a remote σ-activation.
Original language | English |
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Pages (from-to) | 12807-12810 |
Number of pages | 4 |
Journal | Chemical Communications |
Volume | 51 |
Issue number | 64 |
Early online date | 6 Jul 2015 |
DOIs | |
Publication status | Published - 18 Aug 2015 |