Catalysis in enzyme crystals

J. Hajdu, K. R. Acharya, D. I. Stuart, D. Barford, L. N. Johnson

Research output: Contribution to journalArticlepeer-review

Abstract

New developments in X-ray crystallography may produce three-dimensional movies of catalysis and structural changes.

Original languageEnglish
Pages (from-to)104-109
Number of pages6
JournalTrends in Biochemical Sciences
Volume13
Issue number3
DOIs
Publication statusPublished - 1 Jan 1988

Funding

Acknowledgement The authors' research was supported by the US National Science Foundation and the National Institutes of Health. Acknowledgements This work was supported by the Medical Research Council and the Science and Engineering Research Council. We thank our colleagues N. G. Oikonomakos, P. J. McLaughlin and K. Varvili for their contributions to the phosphorylase work and D. R. Trentham for collaboration with the caged phosphates. We also wish to show our appreciation to the staff of the Daresbury Laboratory for the facilities and service and to P. A. Machin, J. W. Campbell, T. J. Greenough, I. J. Cliftron, S. Zurek, S. Gover, J. R. Helliwell, R. C. Liddington and M. Elder for their contributions to the Laue work.

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology

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