Carbon black nanospheres modified with Cu (II)-phthalocyanine for electrochemical determination of Trimethoprim antibiotic

Thais T. Guaraldo, Lorena A. Goulart, Fernando C. Moraes, Marcos R.V. Lanza

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43 Citations (SciVal)


This work investigates the electrochemical sensing properties of glassy carbon (GC) electrodes modified with Printex L6 carbon black (PC) and copper (II) phthalocyanine (CuPh) films. Successful incorporation of the CuPh into carbon black was confirmed by FEG-SEM, EDS and TEM analysis. The transition from nanocrystalline graphite to amorphous carbon material could be evidenced for Printex L6 carbon black using Raman analysis. The modified material (CuPh/PC/GC) demonstrated electrocatalytic effect towards TMP detection according to cyclic voltammetric studies. CuPh modification resulted in strong adsorption to carbon black and TMP due to π-π interactions. Scan rate studies proved reactions across the electrode/electrolyte interface progressively change from adsorption to diffusion. The developed method presented linear relationship in the ranges of 0.4–1.1 µmol L −1 and 1.5–6.0 µmol L −1 with limit of detection of 0.6 µmol L −1 under optimized experimental conditions. The proposed CuPh/PC/GC electrode was effectively employed towards the detection of TMP in natural water samples.

Original languageEnglish
Pages (from-to)555-564
Number of pages10
JournalApplied Surface Science
Early online date24 Nov 2018
Publication statusPublished - 15 Mar 2019

Bibliographical note

Funding Information:
The authors would like to express their sincerest gratitude and indebtedness to the Brazilian Research Funding Agencies including grants #2014/11861-0 , #2014/50945-4 , #2016/01937-4 , #2016/08760-2 and 2017/10118-0 from São Paulo Research Foundation (FAPESP) ) and CNPq for the financial support provided during the course of this work. This study was financed in part by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - Brasil (CAPES) - Finance Code 001. We thank also LMA-LIEC in Araraquara/SP/Brazil for providing the FEG-SEM facilities and Dr. Daniel F. Segura for art work support.

Publisher Copyright:
© 2018 Elsevier B.V.


  • Carbon black
  • Copper phthalocyanine
  • Environmental samples
  • Printex L6
  • Trimethoprim determination

ASJC Scopus subject areas

  • General Chemistry
  • Condensed Matter Physics
  • General Physics and Astronomy
  • Surfaces and Interfaces
  • Surfaces, Coatings and Films


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