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C7β-Methyl Analogues of the Orvinols: The Discovery of Kappa Opioid Antagonists with Nociceptin/Orphanin FQ Peptide (NOP) Receptor Partial Agonism and Low, or Zero, Efficacy at Mu Opioid Receptors

  • Juan Pablo Cueva
  • , Christopher Roche
  • , Mehrnoosh Ostovar
  • , Vinod Kumar
  • , Mary J. Clark
  • , Todd M. Hillhouse
  • , John W. Lewis
  • , John R. Traynor
  • , Stephen M. Husbands
  • University of Michigan

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