Bye-bye muscle biopsy, we have autoantibodies with us now

Victoria Riddell, Sarah Tansley

Research output: Contribution to journalArticlepeer-review

1 Citation (SciVal)


Muscle biopsy is generally considered the gold standard diagnostic tool for patients with presenting with features suggestive of idiopathic inflammatory myopathy. Muscle biopsy is however an invasive test, the histopathological findings can be influenced by previous treatment and not all patients with myositis spectrum disease have muscle involvement. Myositis specific and associated autoantibodies can now be identified in the majority of patients with myositis. When present they identify homogeneous patient subgroups and have the potential to be key tools in developing a personalised approach to disease management. Here we review the utility of myositis specific and associated autoantibodies as diagnostic and prognostic tools.

Original languageEnglish
Pages (from-to)74-80
Number of pages7
JournalIndian Journal of Rheumatology
Issue number6
Publication statusPublished - 30 Jun 2020

Bibliographical note

Publisher Copyright:
© 2020 Indian Journal of Rheumatology.


  • Autoantibody
  • biopsy
  • diagnosis
  • myopathy
  • myositis

ASJC Scopus subject areas

  • Rheumatology


Dive into the research topics of 'Bye-bye muscle biopsy, we have autoantibodies with us now'. Together they form a unique fingerprint.

Cite this