Brønsted Acid-Catalysed Dehydrative Substitution Reactions of Alcohols

James Edward Taylor, Susana Estopina-Duran

Research output: Contribution to journalReview articlepeer-review

42 Citations (SciVal)
56 Downloads (Pure)


The direct, catalytic dehydrative substitution of alcohols is a challenging, yet highly desirable process in the development of more sustainable approaches to organic chemistry. This review outlines recent advances in Brønsted acid-catalysed dehydrative substitution reactions for C-C, C-O, C-N and C-S bond formation. The wide range of processes that are now accessible using simple alcohols as the formal electrophile are highlighted, while current limitations and therefore possible future directions for research are also discussed.
Original languageEnglish
Pages (from-to)106-120
Number of pages15
JournalChemistry - A European Journal
Issue number1
Early online date3 Jun 2020
Publication statusPublished - 4 Jan 2021


  • Brønsted acid
  • alcohols
  • dehydrative substitution
  • homogeneous catalysis
  • sustainable synthesis

ASJC Scopus subject areas

  • Catalysis
  • Organic Chemistry


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