Borrowing hydrogen: iridium-catalysed reactions for the formation of C-C bonds from alcohols

Phillip J Black; Gerta Cami-Kobeci; Michael G Edwards; Paul A Slatford; Michael K Whittlesey; Jonathan M J Williams

doi:10.1039/b511053j

Borrowing hydrogen: iridium-catalysed reactions for the formation of C-C bonds from alcohols

Phillip J Black
, Gerta Cami-Kobeci
, Michael G Edwards
, Paul A Slatford
, Michael K Whittlesey
, Jonathan M J Williams

University of Oxford

Research output: Contribution to journal › Article › peer-review

Abstract

Alcohols have been employed as substrates for C-C bond-forming reactions which involve initial activation by the temporary removal of hydrogen to form an aldehyde. The intermediate aldehyde is converted into an alkene via a Horner-Wadsworth-Emmons reaction, nitroaldol and aldol reactions. The 'borrowed hydrogen' is then returned to the alkene to form a C-C bond.

Original language	English
Pages (from-to)	116-25
Number of pages	10
Journal	Organic and Biomolecular Chemistry
Volume	4
Issue number	1
DOIs	https://doi.org/10.1039/b511053j
Publication status	Published - 7 Jan 2006

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title = "Borrowing hydrogen: iridium-catalysed reactions for the formation of C-C bonds from alcohols",

abstract = "Alcohols have been employed as substrates for C-C bond-forming reactions which involve initial activation by the temporary removal of hydrogen to form an aldehyde. The intermediate aldehyde is converted into an alkene via a Horner-Wadsworth-Emmons reaction, nitroaldol and aldol reactions. The 'borrowed hydrogen' is then returned to the alkene to form a C-C bond.",

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AU - Cami-Kobeci, Gerta

AU - Edwards, Michael G

AU - Slatford, Paul A

AU - Whittlesey, Michael K

AU - Williams, Jonathan M J

PY - 2006/1/7

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AB - Alcohols have been employed as substrates for C-C bond-forming reactions which involve initial activation by the temporary removal of hydrogen to form an aldehyde. The intermediate aldehyde is converted into an alkene via a Horner-Wadsworth-Emmons reaction, nitroaldol and aldol reactions. The 'borrowed hydrogen' is then returned to the alkene to form a C-C bond.

U2 - 10.1039/b511053j

DO - 10.1039/b511053j

M3 - Article

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SP - 116

EP - 125

JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

IS - 1

ER -

Borrowing hydrogen: iridium-catalysed reactions for the formation of C-C bonds from alcohols

Abstract

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