Borrowing hydrogen: iridium-catalysed reactions for the formation of C-C bonds from alcohols

Phillip J Black, Gerta Cami-Kobeci, Michael G Edwards, Paul A Slatford, Michael K Whittlesey, Jonathan M J Williams

Research output: Contribution to journalArticle

Abstract

Alcohols have been employed as substrates for C-C bond-forming reactions which involve initial activation by the temporary removal of hydrogen to form an aldehyde. The intermediate aldehyde is converted into an alkene via a Horner-Wadsworth-Emmons reaction, nitroaldol and aldol reactions. The 'borrowed hydrogen' is then returned to the alkene to form a C-C bond.

Original languageEnglish
Pages (from-to)116-25
Number of pages10
JournalOrganic and Biomolecular Chemistry
Volume4
Issue number1
DOIs
Publication statusPublished - 7 Jan 2006

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