Borrowing hydrogen: iridium-catalysed reactions for the formation of C-C bonds from alcohols

Phillip J Black; Gerta Cami-Kobeci; Michael G Edwards; Paul A Slatford; Michael K Whittlesey; Jonathan M J Williams

doi:10.1039/b511053j

Borrowing hydrogen: iridium-catalysed reactions for the formation of C-C bonds from alcohols

Phillip J Black, Gerta Cami-Kobeci, Michael G Edwards, Paul A Slatford, Michael K Whittlesey, Jonathan M J Williams

University of Oxford

Research output: Contribution to journal › Article › peer-review

Abstract

Alcohols have been employed as substrates for C-C bond-forming reactions which involve initial activation by the temporary removal of hydrogen to form an aldehyde. The intermediate aldehyde is converted into an alkene via a Horner-Wadsworth-Emmons reaction, nitroaldol and aldol reactions. The 'borrowed hydrogen' is then returned to the alkene to form a C-C bond.

Original language	English
Pages (from-to)	116-25
Number of pages	10
Journal	Organic and Biomolecular Chemistry
Volume	4
Issue number	1
DOIs	https://doi.org/10.1039/b511053j
Publication status	Published - 7 Jan 2006

Access to Document

10.1039/b511053j

Cite this

@article{8bcf408ea78343f298dc41bdcf293db8,

title = "Borrowing hydrogen: iridium-catalysed reactions for the formation of C-C bonds from alcohols",

abstract = "Alcohols have been employed as substrates for C-C bond-forming reactions which involve initial activation by the temporary removal of hydrogen to form an aldehyde. The intermediate aldehyde is converted into an alkene via a Horner-Wadsworth-Emmons reaction, nitroaldol and aldol reactions. The 'borrowed hydrogen' is then returned to the alkene to form a C-C bond.",

author = "Black, {Phillip J} and Gerta Cami-Kobeci and Edwards, {Michael G} and Slatford, {Paul A} and Whittlesey, {Michael K} and Williams, {Jonathan M J}",

year = "2006",

month = jan,

day = "7",

doi = "10.1039/b511053j",

language = "English",

volume = "4",

pages = "116--25",

journal = "Organic and Biomolecular Chemistry",

issn = "1477-0520",

publisher = "Royal Society of Chemistry",

number = "1",

}

TY - JOUR

T1 - Borrowing hydrogen

T2 - iridium-catalysed reactions for the formation of C-C bonds from alcohols

AU - Black, Phillip J

AU - Cami-Kobeci, Gerta

AU - Edwards, Michael G

AU - Slatford, Paul A

AU - Whittlesey, Michael K

AU - Williams, Jonathan M J

PY - 2006/1/7

Y1 - 2006/1/7

N2 - Alcohols have been employed as substrates for C-C bond-forming reactions which involve initial activation by the temporary removal of hydrogen to form an aldehyde. The intermediate aldehyde is converted into an alkene via a Horner-Wadsworth-Emmons reaction, nitroaldol and aldol reactions. The 'borrowed hydrogen' is then returned to the alkene to form a C-C bond.

AB - Alcohols have been employed as substrates for C-C bond-forming reactions which involve initial activation by the temporary removal of hydrogen to form an aldehyde. The intermediate aldehyde is converted into an alkene via a Horner-Wadsworth-Emmons reaction, nitroaldol and aldol reactions. The 'borrowed hydrogen' is then returned to the alkene to form a C-C bond.

U2 - 10.1039/b511053j

DO - 10.1039/b511053j

M3 - Article

C2 - 16358005

SN - 1477-0520

VL - 4

SP - 116

EP - 125

JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

IS - 1

ER -

Borrowing hydrogen: iridium-catalysed reactions for the formation of C-C bonds from alcohols

Abstract

Access to Document

Fingerprint

Cite this