Boronic acid building blocks: tools for sensing and separation

Ryuhei Nishiyabu, Yuji Kubo, Tony D. James, John S. Fossey

Research output: Contribution to journalArticle

329 Citations (Scopus)

Abstract

In this feature article the use of boronic acids to monitor, identify and isolate analytes within physiological, environmental and industrial scenarios is discussed. Boronic acids recognise diol motifs through boronic ester formation and interact with anions generating boronates, as such they have been exploited in sensing and separation protocols for diol appended molecules such as saccharides and anions alike. Therefore robust molecular sensors with the capacity to detect chosen molecules selectively and signal their presence continues to attract substantial attention, and boronic acids have been exploited with some success to monitor the presence of various analytes. Reversible boronic acid-diol interactions have also been exploited in boron affinity chromatography realising new separation domains through the same binding events. Boronic acid diol and anion interactions pertaining to sensing and separation are surveyed.
Original languageEnglish
Pages (from-to)1106-1123
Number of pages18
JournalChemical Communications
Volume47
Issue number4
DOIs
Publication statusPublished - 28 Jan 2011

Fingerprint Dive into the research topics of 'Boronic acid building blocks: tools for sensing and separation'. Together they form a unique fingerprint.

  • Cite this