Boronate based fluorescence (ESIPT) probe for peroxynitrite

Adam Sedgwick, Xiaolong Sun, Gyoungmi Kim, Juyoung Yoon, Steven D. Bull, Tony D. James

Research output: Contribution to journalArticle

71 Citations (Scopus)

Abstract

A simple probe for the detection of peroxynitrite was developed incorporating a benzyl boronic ester “protecting” unit. The “protecting” unit of the probe is removed by peroxynitrite to “turn-on” ESIPT fluorescence (4.5 fold enhancement). Furthermore, the probe was cell permeable and was used in cell imaging experiments showing an off–on response towards peroxynitrite, in HeLa and RAW 264.7 cells.
Original languageEnglish
Pages (from-to)12350-12352
Number of pages3
JournalChemical Communications
Volume52
Issue number83
Early online date19 Sep 2016
DOIs
Publication statusPublished - 25 Oct 2016

Fingerprint Dive into the research topics of 'Boronate based fluorescence (ESIPT) probe for peroxynitrite'. Together they form a unique fingerprint.

Cite this