Biotinylated boronic acid fluorophore conjugates: quencher elimination strategy for imaging and saccharide detection

Francois D'Hooge; Souad A Elfeky; Stephen Flower; Sofia I Pascu; A Toby A Jenkins; Johannes van den Elsen; Tony James; John Fossey

doi:10.1039/C2RA00542E

Biotinylated boronic acid fluorophore conjugates: quencher elimination strategy for imaging and saccharide detection

Francois D'Hooge
, Souad A Elfeky
, Stephen Flower
, Sofia I Pascu
, A Toby A Jenkins
, Johannes van den Elsen
, Tony James
, John Fossey

Research output: Contribution to journal › Article › peer-review

21 Citations (SciVal)

Abstract

A biotinylated boronic acid fluorophore conjugate bound to a diol-quencher via a boronic ester linkage demonstrated a fluorescence increase upon exposure to model saccharides. The sensing motif was attached to SuperAvidin microspheres where the sensing regime was imaged by fluorescence microscopy.

Original language	English
Pages (from-to)	3274-3280
Number of pages	7
Journal	RSC Advances
Volume	2
DOIs	https://doi.org/10.1039/C2RA00542E
Publication status	Published - 2012

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10.1039/C2RA00542E

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title = "Biotinylated boronic acid fluorophore conjugates: quencher elimination strategy for imaging and saccharide detection",

abstract = "A biotinylated boronic acid fluorophore conjugate bound to a diol-quencher via a boronic ester linkage demonstrated a fluorescence increase upon exposure to model saccharides. The sensing motif was attached to SuperAvidin microspheres where the sensing regime was imaged by fluorescence microscopy.",

author = "Francois D'Hooge and Elfeky, \{Souad A\} and Stephen Flower and Pascu, \{Sofia I\} and Jenkins, \{A Toby A\} and \{van den Elsen\}, Johannes and Tony James and John Fossey",

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doi = "10.1039/C2RA00542E",

language = "English",

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journal = "RSC Advances",

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AU - D'Hooge, Francois

AU - Elfeky, Souad A

AU - Flower, Stephen

AU - Pascu, Sofia I

AU - Jenkins, A Toby A

AU - van den Elsen, Johannes

AU - James, Tony

AU - Fossey, John

PY - 2012

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AB - A biotinylated boronic acid fluorophore conjugate bound to a diol-quencher via a boronic ester linkage demonstrated a fluorescence increase upon exposure to model saccharides. The sensing motif was attached to SuperAvidin microspheres where the sensing regime was imaged by fluorescence microscopy.

UR - https://www.scopus.com/pages/publications/84859359123

UR - http://dx.doi.org/10.1039/C2RA00542E

U2 - 10.1039/C2RA00542E

DO - 10.1039/C2RA00542E

M3 - Article

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VL - 2

SP - 3274

EP - 3280

JO - RSC Advances

JF - RSC Advances

ER -

Biotinylated boronic acid fluorophore conjugates: quencher elimination strategy for imaging and saccharide detection

Abstract

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A Calibration Free Continuous Invasive Sensor Targeted at Glycaemic Control in the ICU

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Biotinylated boronic acid fluorophore conjugates: quencher elimination strategy for imaging and saccharide detection

Abstract

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A Calibration Free Continuous Invasive Sensor Targeted at Glycaemic Control in the ICU

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