A biotinylated boronic acid fluorophore conjugate bound to a diol-quencher via a boronic ester linkage demonstrated a fluorescence increase upon exposure to model saccharides. The sensing motif was attached to SuperAvidin microspheres where the sensing regime was imaged by fluorescence microscopy.
D'Hooge, F., Elfeky, S. A., Flower, S., Pascu, S. I., Jenkins, A. T. A., van den Elsen, J., James, T., & Fossey, J. (2012). Biotinylated boronic acid fluorophore conjugates: quencher elimination strategy for imaging and saccharide detection. RSC Advances, 2, 3274-3280. https://doi.org/10.1039/C2RA00542E