Biotinylated boronic acid fluorophore conjugates: quencher elimination strategy for imaging and saccharide detection

Francois D'Hooge, Souad A Elfeky, Stephen Flower, Sofia I Pascu, A Toby A Jenkins, Johannes van den Elsen, Tony James, John Fossey

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

A biotinylated boronic acid fluorophore conjugate bound to a diol-quencher via a boronic ester linkage demonstrated a fluorescence increase upon exposure to model saccharides. The sensing motif was attached to SuperAvidin microspheres where the sensing regime was imaged by fluorescence microscopy.
Original languageEnglish
Pages (from-to)3274-3280
Number of pages7
JournalRSC Advances
Volume2
DOIs
Publication statusPublished - 2012

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