Biomimetic flavin-catalyzed aldehyde oxidation

Alexander T. Murray, Pascal Matton, Nathan W. G. Fairhurst, Matthew P. John, David R. Carbery

Research output: Contribution to journalArticle

39 Citations (Scopus)
61 Downloads (Pure)

Abstract

The oxidation of alkyl and aryl aldehydes to their corresponding carboxylic acids has been achieved through the action of a biomimetic bridged flavin catalyst. The reaction uses readily available 35% aqueous hydrogen peroxide and is operationally simple. The oxidation is a green and sustainable reaction, obviating chlorinated solvents with minimal byproducts.
Original languageEnglish
Pages (from-to)3656-3659
Number of pages4
JournalOrganic Letters
Volume14
Issue number14
Early online date10 Jul 2012
DOIs
Publication statusPublished - 20 Jul 2012

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Biomimetics
biomimetics
Carboxylic Acids
aldehydes
Aldehydes
Hydrogen Peroxide
Oxidation
oxidation
hydrogen peroxide
carboxylic acids
Byproducts
catalysts
Catalysts
4,6-dinitro-o-cresol

Cite this

Murray, A. T., Matton, P., Fairhurst, N. W. G., John, M. P., & Carbery, D. R. (2012). Biomimetic flavin-catalyzed aldehyde oxidation. Organic Letters, 14(14), 3656-3659. https://doi.org/10.1021/ol301496m

Biomimetic flavin-catalyzed aldehyde oxidation. / Murray, Alexander T.; Matton, Pascal; Fairhurst, Nathan W. G.; John, Matthew P.; Carbery, David R.

In: Organic Letters, Vol. 14, No. 14, 20.07.2012, p. 3656-3659.

Research output: Contribution to journalArticle

Murray, AT, Matton, P, Fairhurst, NWG, John, MP & Carbery, DR 2012, 'Biomimetic flavin-catalyzed aldehyde oxidation', Organic Letters, vol. 14, no. 14, pp. 3656-3659. https://doi.org/10.1021/ol301496m
Murray AT, Matton P, Fairhurst NWG, John MP, Carbery DR. Biomimetic flavin-catalyzed aldehyde oxidation. Organic Letters. 2012 Jul 20;14(14):3656-3659. https://doi.org/10.1021/ol301496m
Murray, Alexander T. ; Matton, Pascal ; Fairhurst, Nathan W. G. ; John, Matthew P. ; Carbery, David R. / Biomimetic flavin-catalyzed aldehyde oxidation. In: Organic Letters. 2012 ; Vol. 14, No. 14. pp. 3656-3659.
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