Bioavailability and bioequivalence of topical glucocorticoids

S Wiedersberg; C S Leopold; R H Guy

doi:10.1016/j.ejpb.2007.08.007

Bioavailability and bioequivalence of topical glucocorticoids

S Wiedersberg
, C S Leopold
, R H Guy

Department of Life Sciences

Research output: Contribution to journal › Article › peer-review

148 Citations (SciVal)

Abstract

Dermatological therapy depends significantly upon the use of topical glucocorticoids (TG). While effective, and often remarkably so, their delivery into the skin is sometimes rather inefficient. The factors which determine drug efficacy, and the various methodologies, by which the rate and extent of TG transport to their sites of action may be assessed, are the foci of this review.

Original language	English
Pages (from-to)	453-466
Number of pages	14
Journal	European Journal of Pharmaceutics and Biopharmaceutics
Volume	68
Issue number	3
DOIs	https://doi.org/10.1016/j.ejpb.2007.08.007
Publication status	Published - Mar 2008

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10.1016/j.ejpb.2007.08.007

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title = "Bioavailability and bioequivalence of topical glucocorticoids",

abstract = "Dermatological therapy depends significantly upon the use of topical glucocorticoids (TG). While effective, and often remarkably so, their delivery into the skin is sometimes rather inefficient. The factors which determine drug efficacy, and the various methodologies, by which the rate and extent of TG transport to their sites of action may be assessed, are the foci of this review.",

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year = "2008",

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AU - Wiedersberg, S

AU - Leopold, C S

AU - Guy, R H

PY - 2008/3

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N2 - Dermatological therapy depends significantly upon the use of topical glucocorticoids (TG). While effective, and often remarkably so, their delivery into the skin is sometimes rather inefficient. The factors which determine drug efficacy, and the various methodologies, by which the rate and extent of TG transport to their sites of action may be assessed, are the foci of this review.

AB - Dermatological therapy depends significantly upon the use of topical glucocorticoids (TG). While effective, and often remarkably so, their delivery into the skin is sometimes rather inefficient. The factors which determine drug efficacy, and the various methodologies, by which the rate and extent of TG transport to their sites of action may be assessed, are the foci of this review.

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UR - http://dx.doi.org/10.1016/j.ejpb.2007.08.007

U2 - 10.1016/j.ejpb.2007.08.007

DO - 10.1016/j.ejpb.2007.08.007

M3 - Article

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VL - 68

SP - 453

EP - 466

JO - European Journal of Pharmaceutics and Biopharmaceutics

JF - European Journal of Pharmaceutics and Biopharmaceutics

IS - 3

ER -

Bioavailability and bioequivalence of topical glucocorticoids

Abstract

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