Bio-inspired hardware central pattern generator (hCPG) as a therapy for cardiorespiratory disease

Ashok Chauhan; Le Zhao; Julian Paton; Alain Nogaret

doi:10.4108/eai.3-12-2015.2262517

Bio-inspired hardware central pattern generator (hCPG) as a therapy for cardiorespiratory disease

Ashok Chauhan, Le Zhao, Julian Paton, Alain Nogaret

University of Bristol

Research output: Chapter or section in a book/report/conference proceeding › Chapter in a published conference proceeding

Abstract

We report on a hCPG device, which is a network of silicon neurons, and its applications to cardiorespiratory therapy. We study the chaotic dynamics of neurons that compete through mutually inhibitory synapses and demonstrate the emergence of multistable behavior. We were able to select the spatio-Temporal sequences associated with stable modes of oscillation by imparting different initial conditions with timed current steps mimicking delayed stimuli. We constructed the phase lag maps of the hCPG for various connectivities of the network. We also describe a simpler two neuron hCPG which generates a two-phase rhythmic pattern for vagus nerve stimulation and modulation of heart rate by respiration to obtain artificial respiratory sinus-Arrhythmia (RSA).

Original language	English
Title of host publication	BICT 2015 - 9th EAI International Conference on Bio-Inspired Information and Communications Technologies
Publisher	Association for Computing Machinery
ISBN (Electronic)	9781631901003
DOIs	https://doi.org/10.4108/eai.3-12-2015.2262517
Publication status	Published - 24 May 2016
Event	9th EAI International Conference on Bio-Inspired Information and Communications Technologies, BICT 2015 - New York City, USA United States Duration: 3 Dec 2015 → 5 Dec 2015

Conference

Conference	9th EAI International Conference on Bio-Inspired Information and Communications Technologies, BICT 2015
Country/Territory	USA United States
City	New York City
Period	3/12/15 → 5/12/15

Funding

The authors would like to thank British Heart Foundation for supporting this work under grant NH/14/1/30761.

Keywords

Hardware central pattern generator (hCPG)
Silicon neurons

ASJC Scopus subject areas

Computer Science Applications
Software
Biotechnology

Access to Document

10.4108/eai.3-12-2015.2262517

Cite this

Bio-inspired hardware central pattern generator (hCPG) as a therapy for cardiorespiratory disease. / Chauhan, Ashok; Zhao, Le; Paton, Julian et al.
BICT 2015 - 9th EAI International Conference on Bio-Inspired Information and Communications Technologies. Association for Computing Machinery, 2016.

Research output: Chapter or section in a book/report/conference proceeding › Chapter in a published conference proceeding

Chauhan, A, Zhao, L, Paton, J & Nogaret, A 2016, Bio-inspired hardware central pattern generator (hCPG) as a therapy for cardiorespiratory disease. in BICT 2015 - 9th EAI International Conference on Bio-Inspired Information and Communications Technologies. Association for Computing Machinery, 9th EAI International Conference on Bio-Inspired Information and Communications Technologies, BICT 2015, New York City, USA United States, 3/12/15. https://doi.org/10.4108/eai.3-12-2015.2262517

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Bio-inspired hardware central pattern generator (hCPG) as a therapy for cardiorespiratory disease

Abstract

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Funding

Keywords

ASJC Scopus subject areas

Access to Document

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