Barrett's esophagus: Cancer and molecular biology

Michael K.  Gibson; Arashinder S. Dhaliwal; Nicholas J.  Clemons; Wayne A. Phillips; Katerina Dvorak; Daniel Tong; Simon Law; E. Daniel Pirchi; Jari Rasanen; Mark J.  Krasna; Kaushal Parikh; Kausilia K. Krishnadath; Yu Chen; Leonard Griffiths; Benjamin J. Colleypriest; J. Mark Farrant; David Tosh; Kiron M.  Das; Manisha Bajpai

doi:10.1111/nyas.12252

Barrett's esophagus: Cancer and molecular biology

Michael K. Gibson , Arashinder S. Dhaliwal, Nicholas J. Clemons , Wayne A. Phillips, Katerina Dvorak, Daniel Tong , Simon Law, E. Daniel Pirchi , Jari Rasanen, Mark J. Krasna , Kaushal Parikh, Kausilia K. Krishnadath , Yu Chen, Leonard Griffiths, Benjamin J. Colleypriest, J. Mark Farrant, David Tosh, Kiron M. Das , Manisha Bajpai

Department of Life Sciences

Research output: Contribution to journal › Article › peer-review

26 Citations (SciVal)

Abstract

The following paper on the molecular biology of Barrett's esophagus (BE) includes commentaries on signaling pathways central to the development of BE including Hh, NF-κB, and IL-6/STAT3; surgical approaches for esophagectomy and classification of lesions by appropriate therapy; the debate over the merits of minimally invasive esophagectomy versus open surgery; outcomes for patients with pharyngolaryngoesophagectomy; the applications of neoadjuvant chemotherapy and chemoradiotherapy; animal models examining the surgical models of BE and esophageal adenocarcinoma; the roles of various morphogens and Cdx2 in BE; and the use of in vitro BE models for chemoprevention studies.

Original language	English
Pages (from-to)	296-314
Number of pages	19
Journal	Annals of the New York Academy of Sciences
Volume	1300
Issue number	1
DOIs	https://doi.org/10.1111/nyas.12252
Publication status	Published - Oct 2013

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Gibson , M. K., Dhaliwal, A. S., Clemons , N. J., Phillips, W. A., Dvorak, K., Tong , D., Law, S., Pirchi , E. D., Rasanen, J., Krasna , M. J., Parikh, K., Krishnadath , K. K., Chen, Y., Griffiths, L., Colleypriest, B. J., Farrant, J. M., Tosh, D., Das , K. M., & Bajpai, M. (2013). Barrett's esophagus: Cancer and molecular biology. Annals of the New York Academy of Sciences, 1300(1), 296-314. https://doi.org/10.1111/nyas.12252

Gibson , MK, Dhaliwal, AS, Clemons , NJ, Phillips, WA, Dvorak, K, Tong , D, Law, S, Pirchi , ED, Rasanen, J, Krasna , MJ, Parikh, K, Krishnadath , KK, Chen, Y, Griffiths, L, Colleypriest, BJ, Farrant, JM, Tosh, D, Das , KM & Bajpai, M 2013, 'Barrett's esophagus: Cancer and molecular biology', Annals of the New York Academy of Sciences, vol. 1300, no. 1, pp. 296-314. https://doi.org/10.1111/nyas.12252

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AU - Tong , Daniel

AU - Law, Simon

AU - Pirchi , E. Daniel

AU - Rasanen, Jari

AU - Krasna , Mark J.

AU - Parikh, Kaushal

AU - Krishnadath , Kausilia K.

AU - Chen, Yu

AU - Griffiths, Leonard

AU - Colleypriest, Benjamin J.

AU - Farrant, J. Mark

AU - Tosh, David

AU - Das , Kiron M.

AU - Bajpai, Manisha

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Barrett's esophagus: Cancer and molecular biology

Abstract

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