Bacteriostatic activity of fluoro-analogues of 5-(2-hydroxyethyl)-4-methylthiazole, a metabolic intermediate in the biosynthesis of thiamine

Gordon Lowe, Barry Potter

Research output: Contribution to journal › Article › peer-review

Abstract

2-Fluoro-5-(2-hydroxyethyl)-4-methylthiazole and 5-(2-fluoroethyl)-4-methylthiazole have been prepared and the latter converted into a fluoro-analogue of thiamine. All three compounds show bacteriostatic activity against E. coli.
Original languageEnglish
Pages (from-to)2026-2028
JournalJournal of the Chemical Society: Perkin Transactions 1
Volume1980
Issue number0
DOIs
Publication statusPublished - 1980

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