Bacteriostatic activity of fluoro-analogues of 5-(2-hydroxyethyl)-4-methylthiazole, a metabolic intermediate in the biosynthesis of thiamine

Gordon Lowe, Barry Potter

Research output: Contribution to journal › Article

Abstract

2-Fluoro-5-(2-hydroxyethyl)-4-methylthiazole and 5-(2-fluoroethyl)-4-methylthiazole have been prepared and the latter converted into a fluoro-analogue of thiamine. All three compounds show bacteriostatic activity against E. coli.
Original languageEnglish
Pages (from-to)2026-2028
JournalJournal of the Chemical Society: Perkin Transactions 1
Volume1980
Issue number0
DOIs
Publication statusPublished - 1980

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Thiamine
Biosynthesis
Escherichia coli
2-(4-methyl-1,3-thiazol-5-yl)ethanol
4-methylthiazole

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Bacteriostatic activity of fluoro-analogues of 5-(2-hydroxyethyl)-4-methylthiazole, a metabolic intermediate in the biosynthesis of thiamine. / Lowe, Gordon; Potter, Barry.

In: Journal of the Chemical Society: Perkin Transactions 1, Vol. 1980, No. 0, 1980, p. 2026-2028.

Research output: Contribution to journal › Article

Lowe, G & Potter, B 1980, 'Bacteriostatic activity of fluoro-analogues of 5-(2-hydroxyethyl)-4-methylthiazole, a metabolic intermediate in the biosynthesis of thiamine', Journal of the Chemical Society: Perkin Transactions 1, vol. 1980, no. 0, pp. 2026-2028. https://doi.org/10.1039/P19800002026
Lowe G, Potter B. Bacteriostatic activity of fluoro-analogues of 5-(2-hydroxyethyl)-4-methylthiazole, a metabolic intermediate in the biosynthesis of thiamine. Journal of the Chemical Society: Perkin Transactions 1. 1980;1980(0):2026-2028. https://doi.org/10.1039/P19800002026
Lowe, Gordon ; Potter, Barry. / Bacteriostatic activity of fluoro-analogues of 5-(2-hydroxyethyl)-4-methylthiazole, a metabolic intermediate in the biosynthesis of thiamine. In: Journal of the Chemical Society: Perkin Transactions 1. 1980 ; Vol. 1980, No. 0. pp. 2026-2028.
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